Oak Lawn, Illinois Clinical Trials

A listing of Oak Lawn, Illinois clinical trials actively recruiting patient volunteers.

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Found 743 clinical trials
Intervention For AYAS With Cancer Risk Syndromes

This research is being done because there is a need to improve cancer risk communication and decision-making among adolescents and young adults. In this study, the investigators are looking at whether using a chatbot and online portal for cancer risk information helps improve communication and decision-making. Over 70,000 adolescents and …

University of Chicago
 (8.8 away) Contact site
  • 0 views
  • 22 Apr, 2021
  • +4 other locations
TAC T-cells for the Treatment of HER2-positive Solid Tumors

TAC01-HER2 is a novel cell therapy that consists of genetically engineered autologous T cells expressing T-cell Antigen Coupler (TAC) that recognizes human epidermal growth factor receptor 2 (HER2). TAC directs T-cells to the targeted antigen (HER2), and once engaged with the target, activates them via the endogenous T cell receptor. …

University of Chicago
 (8.8 away) Contact site
  • 0 views
  • 12 Sep, 2021
  • +2 other locations
Gut Microbiome and Sex as Risk Factors for Kidney Stones After Bariatric Surgery

This is a single-center study that aims to better understand how diet and sex affect the risk of kidney stones in people who have had gastric bypass surgery. Subjects will be asked to follow a special (clinic-provided) diet for six days and come to a research clinic for 3 study …

University of Chicago Medical Center
 (8.8 away) Contact site
  • 0 views
  • 11 May, 2021
  • 1 location
Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Doctors leading this study will give blood tests to head and neck cancer participants during the beginning of chemotherapy treatment (also known as induction therapy) to see if these blood tests can help predict tumor shrinkage after therapy and reduce the amount of additional radiotherapy or chemotherapy treatment the participant …

University of Chicago Medical Center
 (8.8 away) Contact site
  • 0 views
  • 26 Jan, 2021
  • 1 location
Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian

Afuresertib is an AKT inhibitor, a new class of agents under development that may provide physicians with a new clinical option to control platinum resistant ovarian cancer (PROC) progression. Afuresertib plus chemotherapy has demonstrated anti-tumor efficacy and an acceptable safety profile in patients with PROC in a published Phase I/II …

University of Chicago
 (8.8 away) Contact site
  • 10 views
  • 07 Mar, 2021
  • +24 other locations
Drugs Brain and Behavior (DDP)

In this project, we will examine individual differences in the effects of a stimulant drug, methamphetamine (MA), on mesolimbic reward function using fMRI.

University of Chicago
 (8.8 away) Contact site
  • 0 views
  • 27 Jan, 2021
  • 1 location
PLX2853 in Combination With Abiraterone Acetate and Prednisone and in Combination With Olaparib in Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

The purpose of this research study is to evaluate safety, pharmacokinetics, pharmacodynamics and preliminary efficacy of the investigational drug PLX2853 in subjects with Metastatic Castration-Resistant Prostate Cancer (mCRPC)

University of Chicago
 (8.8 away) Contact site
  • 0 views
  • 20 Aug, 2021
  • +7 other locations
A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)

This Phase 3 study will evaluate the efficacy and safety of KSI-301 compared to aflibercept, in participants with neovascular (wet) age-related macular degeneration (wAMD)

University of Chicago
 (8.8 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +65 other locations
Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease

This is a Phase 3, open-label, repeat-dose study designed to assess liver safety, non-liver safety, and efficacy in subjects who previously experienced liver chemistry test abnormalities while treated with tolvaptan and were permanently discontinued from the drug for that reason. Up to 50 eligible subjects will be enrolled and treated …

tolvaptan
chronic kidney disease
hypertension
renal disease
body mass index
University of Chicago Medicine & Biological Sciences
 (8.8 away) Contact site
  • 0 views
  • 03 May, 2021
  • +8 other locations
A Study to Assess ASP0598 Otic Solution Following Topical Application in the Ear in Subjects With Chronic Tympanic Membrane Perforation (CTMP)

The primary purpose of this study is to evaluate the safety and tolerability of ASP0598 Otic Solution. This study will also evaluate the efficacy of ASP0598 otic solution.

University of Chicago
 (8.8 away) Contact site
  • 0 views
  • 08 Sep, 2021
  • +18 other locations