Northbrook, Illinois Clinical Trials

A listing of Northbrook, Illinois clinical trials actively recruiting patient volunteers.

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Found 74 clinical trials
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A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.  

malignancies
administration intravenous
FGFR3
primary tumor
metastasis
Illinois Cancer Specialists
 (8.3 away) Contact site
  • 46 views
  • 14 Dec, 2020
  • +61 other locations
featured
Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

KRAS
pembrolizumab
USOR - Illinois Cancer Specialists - Niles
 (6.7 away) Contact site
  • 0 views
  • 10 Jun, 2021
  • +32 other locations
featured
Arise 2 - A Study of Oral BTD-001 in Adults With Idiopathic Hypersomnia

This is a randomized, placebo-controlled, double-blind, crossover study of oral BTD-001 in adults with Idiopathic Hypersomnia.  

hypersomnia
Fort Wayne Neurology
 (152.5 away) Contact site
  • 607 views
  • 23 Nov, 2020
  • +17 other locations
featured
Phase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in MET

Phase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in MET

Mirati Research Site
 (9.2 away) Contact site
  • 342 views
  • 08 Nov, 2020
  • +37 other locations
A Safety Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis

This is a phase 2 randomized, multi-center, double-blind, vehicle controlled, 90 day, safety, efficacy, and systemic exposure study followed by a 90 day open-label extension of trifarotene cream in adults and adolescents with autosomal recessive ichthyosis with lamellar scale.

NorthShore University HealthSystem
 (7.8 away) Contact site
  • 101 views
  • 12 Mar, 2021
  • +34 other locations
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

antirheumatics
rheumatism
methotrexate
stiffness
Clinic of Robert Hozman/Clinical Investigation Specialists /ID# 228174
 (9.2 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +255 other locations
Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.

Illinois Cancer Specialists
 (8.3 away) Contact site
  • 50 views
  • 01 Apr, 2021
  • +122 other locations
A Study of Bermekimab (JNJ-77474462) in the Treatment of Participants With Moderate to Severe Atopic Dermatitis

The purpose of this study is to evaluate the efficacy and safety of bermekimab in participants with moderate to severe atopic dermatitis (AD).

eczema
topical agents
dupilumab
Arlington Dermatology
 (9.6 away) Contact site
  • 0 views
  • 14 Jun, 2021
  • +46 other locations
A Proof of Concept Study of Pradigastat in Patients With Functional Constipation

The purpose of this study is to evaluate the efficacy, safety, and tolerability of pradigastat 20 and 40 mg as compared to placebo in patients with Functional Constipation.

Evanston Premier Healthcare Research
 (9.2 away) Contact site
  • 0 views
  • 16 May, 2021
  • +24 other locations
Maximizing Outcomes for Preschoolers With Developmental Language Disorders

The objective of the proposed study is to evaluate the efficacy of the Enhanced Milieu Teaching-Sentence Focus (EMT-SF) intervention, implemented by caregivers and interventionists, relative to a control condition enrolling 108 30-month-old children and their caregivers. The central hypothesis is that intervention will result in better overall child language skills …

Northwestern University
 (9.5 away) Contact site
  • 17 views
  • 25 Jan, 2021
  • +1 other locations