Northbrook, Illinois Clinical Trials

A listing of Northbrook, Illinois clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 161 clinical trials
featured
A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

This is an open-label, randomized (1:1), multicenter, Phase 3 clinical trial evaluating the safety and efficacy of nivolumab in combination with investigational agent sitravatinib compared to docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with …

nivolumab
advanced non-squamous non-small cell lung cancer
experimental drug
lung carcinoma
squamous non-small cell lung cancer
Illinois Cancer Specialists - Niles
 (6.7 away) Contact site
  • 213 views
  • 28 Jul, 2021
  • +188 other locations
featured
Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

pembrolizumab
KRAS
USOR - Illinois Cancer Specialists - Niles
 (6.7 away) Contact site
  • 0 views
  • 28 Jul, 2021
  • +40 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
evobrutinib
teriflunomide
Research Site 649
 (0.9 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +270 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
evobrutinib
teriflunomide
Research Site 715
 (9.1 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +258 other locations
Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.

Illinois Cancer Specialists
 (8.3 away) Contact site
  • 50 views
  • 01 Aug, 2021
  • +122 other locations
Efficacy & Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis

The main purpose of the study is to assess the efficacy and safety of nemolizumab after a 16-week treatment period in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD) not adequately controlled with topical treatments.

Galderma Investigational Site
 (9.5 away) Contact site
  • 112 views
  • 19 Jul, 2021
  • +388 other locations
A Study of AKCEA-APOCIII-LRx Administered to Patients With Familial Chylomicronemia Syndrome (FCS)

The purpose of the study is to evaluate the efficacy of AKCEA-APOCIII-LRx as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.

IONIS Investigative Site
 (9.1 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +28 other locations
Safety Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (DME)

This study is intended to assess the safety, tolerability and evidence of pharmacodynamic activity of a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME)

Northwestern University
 (9.5 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +31 other locations
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

antirheumatics
methotrexate
stiffness
rheumatism
Clinic of Robert Hozman/Clinical Investigation Specialists /ID# 228174
 (9.2 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +291 other locations
A Prospective Multi-center Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.

depressive episode
depressive disorder
depressive symptoms
Psychiatric Medicine Associates, LLC
 (8.4 away) Contact site
  • 655 views
  • 01 Aug, 2021
  • +65 other locations