North Chicago, Illinois Clinical Trials

A listing of North Chicago, Illinois clinical trials actively recruiting patient volunteers.

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Found 69 clinical trials
A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for active eosinophilic esophagitis (EoE) in adult participants.

Illinois Gastroenterology Group-Gurnee
 (4.4 away) Contact site
  • 0 views
  • 20 Jul, 2021
  • +49 other locations
Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.

Cancer Treatment Centers of America
 (8.3 away) Contact site
  • 50 views
  • 01 Aug, 2021
  • +122 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

hydrochlorothiazide
metastatic colorectal adenocarcinoma
vitamin d
metastatic colorectal cancer
monoclonal antibodies
AMG Libertyville - Oncology
 (5.6 away) Contact site
  • 65 views
  • 27 Jul, 2021
  • +978 other locations
A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer

This research study is done to test the safety of the new drug selitrectinib in children and adults with cancer having a change in a particular gene (NTRK1, NTRK2 or NTRK3). The drug may treat cancer by interfering with the effect of the NTRK genes on cancer growth. The study …

kidney function test
experimental drug
NTRK
renal function tests
primary tumor
Cancer Treatment Centers of America (CTCA) - Midwestern Regional Medical Center
 (8.3 away) Contact site
  • 1310 views
  • 27 Jul, 2021
  • +78 other locations
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

natriuretic peptide
nt-probnp
diuretic therapy
heart disease
heart failure
Advocate Condell Medical Center
 (5.6 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +778 other locations
Randomized Study in Children and Adolescents With Migraine: Acute Treatment

The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.

migraine in children
erenumab
acute treatment
Capstone Clinical Research
 (5.6 away) Contact site
  • 0 views
  • 02 Aug, 2021
  • +108 other locations
Etrasimod Versus Placebo as Induction Therapy in Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to assess the efficacy of etrasimod on clinical remission in participants with moderately to severely active ulcerative colitis (UC).

remission
endoscopy
Illinois Gastroenterology Group
 (4.4 away) Contact site
  • 12 views
  • 01 Aug, 2021
  • +438 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
hemoglobin a1c
Clinical Investigation Specialists Inc
 (4.4 away) Contact site
  • 593 views
  • 29 Jul, 2021
  • +888 other locations
A Study to Investigate the Safety and Efficacy of Elsubrutinib and Upadacitinib Given Alone or in Combination in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE)

The main objective of this study is to evaluate the safety and efficacy of elsubrutinib, upadacitinib, and ABBV-599 vs placebo for the treatment of signs and symptoms of Systemic Lupus Erythematosus (SLE) in participants with moderately to severely active SLE and to define doses for further development.

cyclosporine
antinuclear antibody
methotrexate
tacrolimus
lupus
Deerbrook Medical Associates /ID# 212251
 (8.8 away) Contact site
  • 413 views
  • 29 Jul, 2021
  • +312 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Northwestern Medicine Lake Forest Hospital
 (6.0 away) Contact site
  • 135 views
  • 01 Aug, 2021
  • +539 other locations