Normal, Illinois Clinical Trials

A listing of Normal, Illinois clinical trials actively recruiting patient volunteers.

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Found 140 clinical trials
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A Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination With Ruxolitinib in Participants With Myelofibrosis

www.MyelofibrosisResearch.com This is a Phase 2 open-label, multicenter study evaluating tolerability and efficacy of navitoclax alone or when added to ruxolitinib in participants with myelofibrosis.

Mid Illinois Hematology & Oncology Associates, Ltd /ID# 230536
 (1.1 away) Contact site
  • 254 views
  • 29 Apr, 2021
  • +134 other locations
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Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis is a type of bone marrow cancer that usually develops slowly and disrupts body's normal production of blood cells. It causes bone marrow scarring, leading to severe anemia that can cause weakness and fatigue. It can also cause a low number of blood-clotting cells called platelets, which increases …

Mid Illinois Hematology & Oncology Associates, Ltd /ID# 224204
 (1.1 away) Contact site
  • 32 views
  • 29 Apr, 2021
  • +148 other locations
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INCB 18424-303: Topical Ruxolitinib Evaluation in Atopic Dermatitis Study 1 (TRuE-AD1)

A Phase 3, randomized (2:2:1), double-blind, 8-week vehicle control efficacy and safety study of ruxolitinib followed by a randomized, double-blind, 44-week long term safety (LTS) extension period.  In the LTS period,  participants initially randomized to vehicle will receive either ruxolitinib 0.75% or 1.5% cream.  All participants will have follow-up assessments …

eczema
atopic dermatitis/eczema
atopic dermatitis
SNEEZE WHEEZE AND ITCH ASSOCIATES LLC
 (0.2 away) Contact site
  • 242 views
  • 14 Dec, 2020
  • +37 other locations
Evaluation of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

This is a randomized, double-blind, placebo-controlled, parallel-arm, Phase 2b adaptive dose-finding study of BLU-5937 in participants with Refractory Chronic Cough (RCC).

Sneeze Wheeze and Itch Associates LLC
 (0.2 away) Contact site
  • 0 views
  • 19 Jul, 2021
  • +132 other locations
Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation with concomitant and adjuvant …

Illinois CancerCare-Bloomington
 (3.9 away) Contact site
  • 167 views
  • 28 Jul, 2021
  • +125 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site 8739
 (1.1 away) Contact site
  • 21 views
  • 01 Aug, 2021
  • +470 other locations
A Study of Benralizumab in Patients With Eosinophilic Esophagitis

The aim of this Phase 3 study is to investigate the use of benralizumab as a treatment for patients with EoE. The effect of doses of benralizumab on EoE histologic signs and symptoms will be assessed over a 52-week treatment period (including a 24-week double-blind placebo-controlled treatment period and a …

Research Site
 (1.1 away) Contact site
  • 1 views
  • 26 Jul, 2021
  • +83 other locations
Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

This randomized phase II trial studies how well ruxolitinib phosphate, and bosutnib, dasatinib, or nilotinib, work in treating patients with chronic myeloid leukemia. Chronic myeloid leukemia cells produce a protein called BCR-ABL. The BCR-ABL protein helps chronic myeloid leukemia cells to grow and divide. Tyrosine kinase inhibitors, such as bosutinib, …

Illinois CancerCare-Bloomington
 (3.9 away) Contact site
  • 38 views
  • 11 May, 2021
  • +441 other locations
Lateral Branch Cooled Radiofrequency Denervation vs. Conservative Therapy for Sacroiliac Joint Pain

This is a prospective, randomized, controlled, multi-center clinical study. Approximately 208 subjects will be enrolled at approximately 12-15 active duty military, veterans' care, and civilian sites. Eligible subjects will be randomized in 1:1 ratio to receive either Sacroiliac denervation using CRF (treatment group) or standard medical management ("SMM," control group).

Millennium Pain Center
 (3.9 away) Contact site
  • 15 views
  • 22 Mar, 2021
  • +16 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

vitamin d
rifampin
major surgery
tumor cells
measurable disease
Illinois CancerCare-Bloomington
 (3.9 away) Contact site
  • 65 views
  • 27 Jul, 2021
  • +978 other locations