Naperville, Illinois Clinical Trials

A listing of Naperville, Illinois clinical trials actively recruiting patient volunteers.

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Found 242 clinical trials
Changes in NT-proBNP and Outcomes Safety and Tolerability in HFpEF Patients With Acute Decompensated Heart Failure (ADHF) Who Have Been Stabilized During Hospitalization and Initiated In-hospital or Within 30 Days Post-discharge (PARAGLIDE-HF)

The purpose of this study is to assess the effect of sacubitril/valsartan (LCZ696) vs. valsartan on changes in NT-proBNP and outcomes, safety and tolerability in patients with HFpEF (left ventricular ejection fraction (LVEF) > 40%) who have been stabilized during hospitalization for acute decompensated heart failure and initiated in-hospital or …

Novartis Investigative Site
 (4.0 away) Contact site
  • 30 views
  • 08 Jul, 2021
  • +93 other locations
A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Platysma Prominence

The purpose of the study is to evaluate the safety and effects of onabotulinumtoxinA (BOTOX) for the temporary improvement in the appearance of platysma prominence. Study doctors will randomize participants into 1 of the 2 groups, called treatment arms. There is a 1 in 2 chance that a participant will …

Oak Dermatology in Naperville /ID# 231193
 (3.6 away) Contact site
  • 25 views
  • 17 Sep, 2021
  • +28 other locations
A Study to Evaluate the Efficacy and Safety of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia

This is a phase 3, multicenter, randomized, double-blinded, placebo-controlled, parallel-group trial to evaluate the efficacy, safety, and effect on QoL/PRO of efgartigimod PH20 SC treatment in adult patients with primary ITP.

Investigator Site 0010079
 (7.5 away) Contact site
  • 9 views
  • 19 Sep, 2021
  • +36 other locations
A Prospective Multi-center Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.

depressive disorder
depressive symptoms
depressive episode
AMR- Baber Research, Inc.
 (2.1 away) Contact site
  • 670 views
  • 19 Sep, 2021
  • +70 other locations
Durvalumab vs Placebo With Stereotactic Body Radiation Therapy in Early Stage Unresected Non-small Cell Lung Cancer Patients

This is a Phase III, randomized, placebo-controlled, double-blind, multi-center study assessing the efficacy and safety of durvalumab with SoC SBRT versus placebo with SoC SBRT in patients with unresected clinical Stage I/II lymph node-negative (T1 to T3N0M0) NSCLC.

lung carcinoma
stereotactic body radiation therapy
durvalumab
Research Site
 (7.0 away) Contact site
  • 72 views
  • 28 Apr, 2021
  • +226 other locations
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to evaluate the efficacy and safety (including evaluating side effects) of combination of olaparib and abiraterone versus placebo and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemotherapy or new hormonal agents (NHAs) at metastatic castration-resistant prostate …

MRI
abiraterone
adenocarcinoma
prostate adenocarcinoma
androgen suppression
Research Site
 (3.0 away) Contact site
  • 200 views
  • 19 Aug, 2021
  • +197 other locations
Evaluation of the CleanSweep Closed Suction System on Length of Mechanical Ventilation and Ventilator-Associated Events

The primary aim of this study is to evaluate the CleanSweep Closed Suction System on time to first successful spontaneous breathing trial in mechanically ventilated patients in the medical intensive care unit. Secondary aims of this study are to evaluate the use endotracheal tube sweeping compared to closed suctioning effect …

Rush University Medical Center
 (7.5 away) Contact site
  • 10 views
  • 01 May, 2021
  • 1 location
The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke

The primary objective of the trial is to establish the effectiveness of IAT (versus medical management) in patients with moderate-large infarcts (NCCT ASPECTS 2-5) at baseline, with adaptive enrichment to better define the upper limit of infarct volume for treatment eligibility. Furthermore, the investigators aim to determine whether certain subgroups …

infarct
thrombectomy
stroke
central DuPage Hospital Association d/b/a Northwestern Medicine Central DuPage Hospital
 (7.2 away) Contact site
  • 69 views
  • 09 Sep, 2021
  • +38 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

solid tumors
platelet count
liver metastasis
cancer
neutrophil count
Northwestern Medicine Cancer Center Warrenville
 (5.0 away) Contact site
  • 83 views
  • 22 Aug, 2021
  • +979 other locations
Hearing Aid Signal Processing Comparative Study

Participants will be fit with each of two hearing instruments in an ABA cross-over design. The study will consist of a total of three approximately 10-day home trials with the devices. Participants will be asked to provide qualitative feedback to investigators regarding the performance of and their preference for each …

Phonak Audiology Research Center
 (4.0 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • 1 location