Macomb, Illinois Clinical Trials

A listing of Macomb, Illinois clinical trials actively recruiting patient volunteers.

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Found 57 clinical trials
Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

This phase II/III trial compares the usual treatment with radiation therapy and temozolomide to radiation therapy in combination with immunotherapy with ipilimumab and nivolumab in treating patients with newly diagnosed MGMT unmethylated glioblastoma. Radiation therapy uses high energy photons to kill tumor and shrink tumors. Chemotherapy drugs, such as temozolomide, …

karnofsky performance status
temozolomide
flair
tumor cells
brain mri
Illinois CancerCare-Carthage
 (24.5 away) Contact site
  • 1 views
  • 26 Sep, 2021
  • +149 other locations
Testing Maintenance Therapy for Small Cell Lung Cancer in Patients With SLFN11 Positive Biomarker

This phase II trial studies whether atezolizumab in combination with talazoparib works better than atezolizumab alone as maintenance therapy for patients with SLFN11-positive extensive-stage small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability …

brain metastases
ct scan
antiretroviral therapy
prednisone
leptomeningeal disease
Illinois CancerCare-Carthage
 (24.5 away) Contact site
  • 0 views
  • 25 Sep, 2021
  • +428 other locations
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer The RAPTOR Trial

This phase II/III trial compares the effect of adding radiation therapy to the usual maintenance therapy with atezolizumab versus atezolizumab alone in patients who have already received atezolizumab plus chemotherapy for the treatment of small cell lung cancer that has spread outside of the lung or to other parts of …

luteinizing hormone
x-rays
brain metastases
ct scan
pleural effusion
Illinois CancerCare-Macomb
 (0.4 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +151 other locations
A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes (The INSPIRE Study)

This phase II trial studies the benefit of adding an immunotherapy drug called MEDI4736 (durvalumab) to standard chemotherapy and radiation therapy in treating bladder cancer which has spread to the lymph nodes. Drugs used in standard chemotherapy work in different ways to stop the growth of tumor cells, either by …

gemcitabine
invasive bladder cancer
bladder tumor
transurethral resection
inspire
Illinois CancerCare-Carthage
 (24.5 away) Contact site
  • 0 views
  • 23 Sep, 2021
  • +157 other locations
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor …

fallopian tube
undifferentiated carcinoma
pleural effusion
international normalized ratio
warfarin
Illinois CancerCare-Macomb
 (0.4 away) Contact site
  • 185 views
  • 26 Sep, 2021
  • +758 other locations
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. …

brain metastases
growth factor
amylase
lipase
ct scan
Illinois CancerCare-Macomb
 (0.4 away) Contact site
  • 191 views
  • 26 Sep, 2021
  • +476 other locations
Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

This phase III trial studies how well chemotherapy and radiation therapy work with or without atezolizumab in treating patients with localized muscle invasive bladder cancer. Radiation therapy uses high energy rays to kill tumor cells and shrink tumors. Chemotherapy drugs, such as gemcitabine, cisplatin, fluorouracil and mitomycin-C, work in different …

gemcitabine
invasive bladder cancer
skin cancer
gilbert's syndrome
bladder tumor
Illinois CancerCare-Macomb
 (0.4 away) Contact site
  • 37 views
  • 26 Sep, 2021
  • +183 other locations
Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors

This phase II trial studies how a diet intervention works in improving bowel dysfunction symptoms related in colon or rectal cancer survivors. Changing a diet may be helpful in reducing the severity of bowel symptoms, including diarrhea and constipation, and improve quality of life in colon or rectal cancer survivors …

rectal carcinoma
inflammatory bowel disease
constipation
cancer
low anterior resection
Illinois CancerCare-Macomb
 (0.4 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +234 other locations
Docetaxel or Paclitaxel in Reducing Chemotherapy-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

This phase II trial studies how well docetaxel or paclitaxel work in reducing chemotherapy-induced peripheral neuropathy in African American patients with stages I-III breast cancer. Drugs used in chemotherapy, such as docetaxel and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, …

docetaxel
progesterone
oophorectomy
taxane
progesterone receptor
Illinois CancerCare-Macomb
 (0.4 away) Contact site
  • 101 views
  • 27 Sep, 2021
  • +396 other locations
Testing the Addition of an Anti-cancer Drug Pembrolizumab to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

This phase II trial studies the effect of adding pembrolizumab to gemcitabine in treating patients with non-muscle invasive bladder cancer whose cancer does not respond to Bacillus Calmette-Guerin (BCG) treatment. Chemotherapy drugs, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the …

Illinois CancerCare-Macomb
 (0.4 away) Contact site
  • 60 views
  • 19 Sep, 2021
  • +301 other locations