Macomb, Illinois Clinical Trials

A listing of Macomb, Illinois clinical trials actively recruiting patient volunteers.

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Found 53 clinical trials
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

revlimid
hypertension
neutrophil count
bortezomib
cancer
Illinois CancerCare-Macomb
 (0.4 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +373 other locations
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage HPV-Positive Non-Smoking Associated Oropharyngeal Cancer

This phase II/III trial studies how well a reduced dose of radiation therapy works with nivolumab compared to cisplatin in treating patients with human papillomavirus (HPV)-positive oropharyngeal cancer that is early in its growth and may not have spread to other parts of the body (early-stage), and is not associated …

metastasis
hepatitis c virus ribonucleic acid
cigarette smoking
nivolumab
hysterectomy
Illinois CancerCare-Macomb
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  • 28 views
  • 19 Sep, 2021
  • +236 other locations
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, …

tubal ligation
monoclonal antibodies
mitomycin
paclitaxel
neutrophil count
Illinois CancerCare-Carthage
 (24.5 away) Contact site
  • 141 views
  • 19 Sep, 2021
  • +590 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

combination chemotherapy
monoclonal antibodies
metastasis
antifungal agents
fluorouracil
Illinois CancerCare-Macomb
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  • 1047 views
  • 19 Sep, 2021
  • +595 other locations
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

This phase III trial compares immunotherapy drugs (nivolumab or brentuximab vedotin) when given with combination chemotherapy in treating patients with newly diagnosed stage III or IV classic Hodgkin lymphoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the …

combination chemotherapy
vinblastine
monoclonal antibodies
classical hodgkin lymphoma
human immunodeficiency virus
Illinois CancerCare-Macomb
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  • 72 views
  • 19 Sep, 2021
  • +511 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Illinois CancerCare-Macomb
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  • 85 views
  • 19 Sep, 2021
  • +347 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

pd-l1
stage iv non-small cell lung cancer
metastasis
monoclonal antibodies
brain imaging
Illinois CancerCare-Carthage
 (24.5 away) Contact site
  • 213 views
  • 19 Sep, 2021
  • +832 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Illinois CancerCare-Macomb
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  • 135 views
  • 16 Sep, 2021
  • +540 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

pd-l1
monoclonal antibodies
metastasis
pembrolizumab
interleukin 2
Illinois CancerCare-Macomb
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  • 157 views
  • 19 Sep, 2021
  • +688 other locations
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer the DECREASE Study

This phase II trial studies how well lower-dose chemotherapy plus radiation (chemoradiation) therapy works in comparison to standard-dose chemoradiation in treating patients with early-stage anal cancer. Drugs used in chemotherapy, such as mitomycin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing …

Illinois CancerCare-Carthage
 (24.5 away) Contact site
  • 11 views
  • 17 Sep, 2021
  • +372 other locations