Lombard, Illinois Clinical Trials

A listing of Lombard, Illinois clinical trials actively recruiting patient volunteers.

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Found 119 clinical trials
The Orchestra Study: An 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

The Orchestra Study (study number PD0053) is a clinical research study for people with early-stage Parkinson’s disease (<2 years). The aim of the study is to find out whether an investigational medication known as UCB0599 can slow the progression of Parkinson’s disease and whether it is efficacious and well tolerated (which means …

dopamine transporter
tremor
SPECT Scan
movement disorder
bradykinesia
Northwestern Memorial Healthcare - Office of Research
 (7.0 away) Contact site
  • 0 views
  • 28 Jul, 2021
  • +22 other locations
Flexible-Dose Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations (TemPo-3)

The purpose of this study is to assess the effect of tavapadon on the change from baseline in total daily hours of "on" time without troublesome dyskinesia in L-Dopa-treated participants with Parkinson's Disease (PD) who are experiencing motor fluctuations.

carbidopa
dyskinesia
amantadine
bradykinesia
carbidopa/levodopa
Neurosciences Research
 (9.4 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +101 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

teriflunomide
evobrutinib
aubagio
Research Site 621
 (9.4 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +270 other locations
Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy

The purpose of this study is to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR). This evaluation will provide information that brolucizumab is non-inferior to PRP with respect to the change in best corrected visual acuity at Week …

Novartis Investigative Site
 (4.0 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +81 other locations
Safety Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19

This is a phase 2 study in which subjects with coronavirus disease 2019 (COVID-19) will receive VIR-7831 (Sotrovimab) Generation 1 (Gen1) or VIR-7831 (Sotrovimab) Generation 2 (Gen2) and will be assessed for safety, tolerability, and pharmacokinetics.

Investigative Site
 (7.0 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +33 other locations
A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy

This study will evaluate the efficacy, safety, pharmacodynamics, and pharmacokinetics (PK) of obinutuzumab compared with tacrolimus in participants with primary membranous nephropathy (pMN).

Loyola University Med Center
 (8.9 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +77 other locations
A Prospective Multi-center Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.

depressive episode
depressive symptoms
depressive disorder
AMR- Baber Research, Inc.
 (9.7 away) Contact site
  • 655 views
  • 01 Aug, 2021
  • +65 other locations
Study of Sasanlimab (PF-06801591) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-Risk Non-Muscle Invasive Bladder Cancer

CREST: Combination of sasanlimab and alternative BCG Regimens to Evaluate outcomes with Subcutaneous anti-PD-1 Treatment Phase 3 Design with 3 study Arms (A, B and C). Arms A and B consists of two study drugs, PF-06801591 plus BCG. Arm C consists of one study drug, BCG. The study is designed …

DuPage Medical Group Ambulatory Surgery Center
 (0.7 away) Contact site
  • 10 views
  • 01 Aug, 2021
  • +218 other locations
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer Compared to Nab-paclitaxel+Gemcitabine Treatment

The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for …

Elmhurst Cancer Center Research
 (4.0 away) Contact site
  • 31 views
  • 01 Aug, 2021
  • +273 other locations
Flexible-Dose Trial in Early Parkinson's Disease (TemPo-2)

The purpose of this study is to assess the efficacy, safety, tolerability and pharmacokinetics (PK) of flexible doses of tavapadon in participants with Parkinson's Disease.

early parkinson's
levodopa
dopa
dopamine agonists
bradykinesia
Neurosciences Research
 (9.4 away) Contact site
  • 7 views
  • 31 Jul, 2021
  • +48 other locations