Lake Villa, Illinois Clinical Trials

A listing of Lake Villa, Illinois clinical trials actively recruiting patient volunteers.

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Found 35 clinical trials
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body (metastatic). Chemotherapy drugs, such as paclitaxel, work in different ways to stop the growth of tumor cells, either …

adenocarcinoma
breast adenocarcinoma
platelet count
monoclonal antibody therapy
estrogen
Midwestern Regional Medical Center
 (9.2 away) Contact site
  • 445 views
  • 23 Sep, 2021
  • +464 other locations
Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

This randomized phase II/III trial studies how well giving maintenance chemotherapy with or without local consolidation therapy works in treating patients with stage IV non-small cell lung cancer. Drugs used in maintenance chemotherapy, such as docetaxel, pemetrexed disodium, erlotinib hydrochloride, and gemcitabine work in different ways to stop the growth …

gemcitabine
lung cancer
stereotactic body radiation therapy
erlotinib
systemic therapy
Condell Memorial Hospital
 (7.3 away) Contact site
  • 238 views
  • 22 Sep, 2021
  • +193 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

mmr protein
adenocarcinoma
antifungal agents
oxaliplatin
antibiotics
NorthShore Hematology Oncology-Libertyville
 (7.3 away) Contact site
  • 1047 views
  • 22 Sep, 2021
  • +595 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

brain metastasis
erdafitinib
heart failure
tubal ligation
adrenaline
Midwestern Regional Medical Center
 (9.2 away) Contact site
  • 6097 views
  • 22 Sep, 2021
  • +1027 other locations
Phase 2 Study of Poziotinib in Patients With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation

This is a Phase 2, open-label, multi-center study to evaluate the efficacy and the safety/tolerability of poziotinib in seven patient cohorts for up to 603 previously treated and treatment-nave NSCLC patients. Cohorts 3 and 4 were added with Amendment 1 and three additional cohorts were added with Amendment 2 (Cohorts …

lung carcinoma
HER2
osimertinib
cancer chemotherapy
EGFR
CTCA - Midwestern Regional Medical Center
 (9.2 away) Contact site
  • 320 views
  • 12 Sep, 2021
  • +70 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Midwestern Regional Medical Center
 (9.2 away) Contact site
  • 85 views
  • 22 Sep, 2021
  • +347 other locations
A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn's disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, …

immunosuppressive agents
certolizumab pegol
crohn's disease
tumor necrosis factor
methotrexate
Illinois Gastroenterology Group
 (4.0 away) Contact site
  • 63 views
  • 18 Sep, 2021
  • +175 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

germ cell tumor
tubal ligation
adrenaline
trophoblastic disease
spindle cell carcinoma of kidney
Midwestern Regional Medical Center
 (9.2 away) Contact site
  • 6048 views
  • 22 Sep, 2021
  • +817 other locations
A Study to Assess the Antitumor Activity and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall survival and assess the safety and tolerability of the combination treatment. This study will also evaluate other anti-tumor effects, tumor markers and pharmacokinetics (PK) of zolbetuximab, …

adenocarcinoma
gemcitabine
pancreatic adenocarcinoma
international normalized ratio
adjuvant therapy
Cancer Treatment Centers of America, Chicago
 (9.2 away) Contact site
  • 233 views
  • 20 Sep, 2021
  • +112 other locations
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease

This study seeks to evaluate the safety and efficacy of brazikumab versus placebo (Stage I) and versus an active comparator (Stage 2) in participants with moderately to severely active CD and will include assessments of clinical response as demonstrated by improvement of symptoms and colonic mucosal appearance as observed on …

antibiotics
crohn's disease
endoscopy
mercaptopurine
immunomodulators
Illinois Gastroenterology Group, LLC
 (2.9 away) Contact site
  • 400 views
  • 20 Sep, 2021
  • +320 other locations