Hoffman Estates, Illinois Clinical Trials

A listing of Hoffman Estates, Illinois clinical trials actively recruiting patient volunteers.

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Found 111 clinical trials
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The PQ Bypass Pivotal IDE Intra-arterial Stent Graft Study for Occlusive and Re-stenotic Fem-pop Revascularization - 2 Trial: TORUS 2

The primary objective of the TORUS 2 IDE Clinical Study is to evaluate the safety and effectiveness of the TORUS Stent Graft System in the treatment of obstructive atherosclerotic lesions of the native SFA or the superficial femoral and/or proximal popliteal arteries.

AMITA Health
 (5.6 away) Contact site
  • 17 views
  • 23 Nov, 2020
  • 1 location
featured
A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.  

solid tumors
malignancies
malignancy
measurable disease
solid tumor
Illinois Cancer Specialists
 (6.2 away) Contact site
  • 46 views
  • 14 Dec, 2020
  • +61 other locations
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Phase 3 Study of MRTX849 vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-12)

This Phase 3 study will evaluate the efficacy of the investigational agent MRTX849 versus docetaxel in patients who have been previously treated for metastatic NSCLC with a KRAS G12C mutation.

lung metastases
recurrent non-small cell lung cancer
refractory non-small cell lung cancer
metastatic non-small cell lung cancer
advanced lung cancer
Mirati Research Site
 (6.3 away) Contact site
  • 0 views
  • 16 Jul, 2021
  • +37 other locations
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A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

The main purpose of this study is to assess the efficacy and safety of daily and intermittent dosing of MK-1942 compared to placebo among participants with Treatment-Resistant Depression (TRD) on a stable course of antidepressant therapy.The dual primary hypotheses of the study are that the daily MK-1942 treatment and/or intermittent …

AMITA Health
 (1.6 away) Contact site
  • 0 views
  • 23 Mar, 2021
  • 1 location
Long Term Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

This is an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305, which also allows participants from the Phase 2 Study 12-AVR-131 to be included.

Behavioral Health Care Associates
 (1.5 away) Contact site
  • 0 views
  • 11 Jul, 2021
  • +296 other locations
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine

The main purpose of this study is to evaluate the efficacy and safety of galcanezumab for the preventive treatment of chronic migraine in participants 12 to 17 years of age. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days …

AMITA Health - Alexian Brothers Neurosciences Institute Clinical Research
 (0.7 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +78 other locations
Flexible-Dose Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations (TemPo-3)

The purpose of this study is to assess the effect of tavapadon on the change from baseline in total daily hours of "on" time without troublesome dyskinesia in L-Dopa-treated participants with Parkinson's Disease (PD) who are experiencing motor fluctuations.

amantadine
levodopa
bradykinesia
carbidopa/levodopa
dopa
Neurosciences Research
 (7.6 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +101 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

evobrutinib
teriflunomide
aubagio
Research Site 628
 (4.7 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +270 other locations
Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.

Illinois Cancer Specialists
 (6.2 away) Contact site
  • 50 views
  • 01 Aug, 2021
  • +122 other locations
Efficacy and Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis

The main purpose of the study is to assess the efficacy and safety of nemolizumab after a 16-week treatment period in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD) not adequately controlled with topical treatments.

Galderma Investigaitonal Site
 (4.8 away) Contact site
  • 95 views
  • 16 Jul, 2021
  • +458 other locations