Highland Park, Illinois Clinical Trials

A listing of Highland Park, Illinois clinical trials actively recruiting patient volunteers.

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Found 55 clinical trials
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

pregnancy test urine
hmr1726
aubagio
teriflunomide
contraceptive use
Investigational Site Number 8400011
 (3.8 away) Contact site
  • 0 views
  • 20 Jul, 2021
  • +120 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
teriflunomide
evobrutinib
Research Site 649
 (3.8 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +261 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

metastasis
open biopsy
folfiri
monoclonal antibodies
metastatic colorectal adenocarcinoma
NorthShore University HealthSystem-Highland Park Hospital
 (0.0 away) Contact site
  • 65 views
  • 22 Jul, 2021
  • +978 other locations
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery …

oophorectomy
skin carcinoma
carcinoma
lobular carcinoma
hemoglobin a1c
Northwestern Medicine Lake Forest Hospital
 (5.3 away) Contact site
  • 335 views
  • 21 Jul, 2021
  • +903 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

metastasis
antibiotics
primary cancer
diabetes
nausea
NorthShore University HealthSystem-Highland Park Hospital
 (0.0 away) Contact site
  • 109 views
  • 21 Jul, 2021
  • +595 other locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

endoscopy
mirikizumab
Gen1 Research - Gastroenterology Consultants of the North Shore
 (7.8 away) Contact site
  • 386 views
  • 21 Jul, 2021
  • +906 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

metastasis
oophorectomy
insulin
monoclonal antibodies
chronic hepatitis b
Northwestern Medicine Lake Forest Hospital
 (5.3 away) Contact site
  • 206 views
  • 15 Jul, 2021
  • +830 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

metastasis
atezolizumab
monoclonal antibodies
systemic therapy
platelet count
Northwestern Medicine Lake Forest Hospital
 (4.5 away) Contact site
  • 157 views
  • 17 Jul, 2021
  • +675 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Northwestern Medicine Lake Forest Hospital
 (4.5 away) Contact site
  • 85 views
  • 21 Jul, 2021
  • +331 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

antifungal agents
metastasis
monoclonal antibody therapy
atezolizumab
monoclonal antibodies
Northwestern Medicine Lake Forest Hospital
 (4.5 away) Contact site
  • 1047 views
  • 21 Jul, 2021
  • +588 other locations