Hazel Crest, Illinois Clinical Trials

A listing of Hazel Crest, Illinois clinical trials actively recruiting patient volunteers.

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Found 126 clinical trials
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).

stemi
acute coronary syndrome
angina pectoris
unstable angina
heart disease
Community Hospital
 (9.6 away) Contact site
  • 350 views
  • 04 May, 2021
  • +112 other locations
Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)

This Phase 3 multinational, randomized, double-blind study is designed to compare the efficacy and safety of the combination of ibrutinib and venetoclax vs. ibrutinib and placebo in subjects with MCL.

cyclin d1
TP53
mantle cell lymphoma
renal function tests
venetoclax
Ingalls Memorial Hospital
 (3.0 away) Contact site
  • 908 views
  • 01 Aug, 2021
  • +179 other locations
Comparing an Operation to Monitoring With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS

This study looks at the risks and benefits of active monitoring (AM) compared to surgery in the setting of a pragmatic prospective randomized trial for low risk DCIS. Our overarching hypothesis is that management of low-risk Ductal Carcinoma in Situ (DCIS) using an AM approach does not yield inferior cancer …

erbb2
endocrine therapy
mastectomy
invasive cancer
mammogram
Ingalls Memorial Hospital
 (3.0 away) Contact site
  • 1212 views
  • 03 Sep, 2021
  • +136 other locations
QUILT 2.023: A Study of N-803 in Combination With Current Standard of Care vs Standard of Care as First-Line Treatment for Patients With Stage 3 or 4 NSCLC.

This is a phase 3, open-label, 3-cohort, randomized study to compare the safety and efficacy of N-803 in combination with the current standard of care (experimental arms) versus standard of care alone (control arms), as first-line treatment for subjects with stage 3 or 4 advanced or metastatic NSCLC. Treatment will …

pembrolizumab
proto-oncogene tyrosine-protein kinase ros
ROS1
tyrosine
gefitinib
Healthcare Research Network
 (7.7 away) Contact site
  • 34 views
  • 05 Aug, 2021
  • +33 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

pembrolizumab
hysterectomy
ROS1
cardiotoxic agents
tubal ligation
University of Chicago Medicine-Orland Park
 (8.2 away) Contact site
  • 213 views
  • 26 Sep, 2021
  • +832 other locations
The Safety and Efficacy of SYD-101 in Children With Myopia

Myopia, or nearsightedness, is the most common eye disorder, often affecting more than 40% of adults in Europe, Asia and the USA. Severe myopia is associated with an increased risk of developing other eye conditions such as glucoma, cataracts and retinal detachment, which may lead to blindness. Early treatment of …

astigmatism
anisometropia
severe myopia
ophthalmic solution
retinal detachment
Site 131
 (9.6 away) Contact site
  • 123 views
  • 25 Jan, 2021
  • +63 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

interleukin 2
metastatic renal cell carcinoma
pembrolizumab
systemic therapy
calcium
Ingalls Memorial Hospital
 (3.2 away) Contact site
  • 157 views
  • 26 Sep, 2021
  • +688 other locations
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted effects) may occur. There are three parts to this study. In Part A, the treatment will be given to participants every 3 weeks (3-week cycles). In …

solid tumour
kinase inhibitor
oxaliplatin
systemic therapy
cancer
Ingalls Cancer Care / Ingalls Memorial Hospital
 (3.0 away) Contact site
  • 226 views
  • 16 Sep, 2021
  • +48 other locations
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

This phase II/III trial studies how well daunorubicin and cytarabine with or without uproleselan works in treating older adult patients with acute myeloid leukemia receiving intensive induction chemotherapy. Drugs used in chemotherapy, such as daunorubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by …

lenalidomide
tyrosine
cytarabine
decitabine
acute promyelocytic leukemia
University of Chicago Medicine-Orland Park
 (8.7 away) Contact site
  • 25 views
  • 26 Sep, 2021
  • +108 other locations
S1803 Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 …

lenalidomide
daratumumab
induction therapy
warfarin
heparin
Loyola Center for Cancer Care and Research
 (8.2 away) Contact site
  • 90 views
  • 07 Mar, 2021
  • +550 other locations