Glenview, Illinois Clinical Trials

A listing of Glenview, Illinois clinical trials actively recruiting patient volunteers.

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Found 146 clinical trials
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Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

KRAS
pembrolizumab
USOR - Illinois Cancer Specialists - Niles
 (3.1 away) Contact site
  • 0 views
  • 28 Jul, 2021
  • +40 other locations
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A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

This is an open-label, randomized (1:1), multicenter, Phase 3 clinical trial evaluating the safety and efficacy of nivolumab in combination with investigational agent sitravatinib compared to docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with …

advanced lung cancer
lung cancer
advanced non-squamous non-small cell lung cancer
lung carcinoma
docetaxel
Illinois Cancer Specialists - Niles
 (3.1 away) Contact site
  • 199 views
  • 28 Jul, 2021
  • +188 other locations
A Study of Bermekimab (JNJ-77474462) in the Treatment of Participants With Moderate to Severe Atopic Dermatitis

The purpose of this study is to evaluate the efficacy and safety of bermekimab in participants with moderate to severe atopic dermatitis (AD).

topical agents
dupilumab
eczema
Arlington Dermatology
 (10.0 away) Contact site
  • 5 views
  • 17 Jul, 2021
  • +47 other locations
Safety Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (DME)

This study is intended to assess the safety, tolerability and evidence of pharmacodynamic activity of a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME)

Northwestern University
 (7.1 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +31 other locations
Flexible-Dose Trial in Early Parkinson's Disease (TemPo-2)

The purpose of this study is to assess the efficacy, safety, tolerability and pharmacokinetics (PK) of flexible doses of tavapadon in participants with Parkinson's Disease.

early parkinson's
dopamine
dopamine agonists
dopa
bradykinesia
Neurosciences Research
 (9.0 away) Contact site
  • 5 views
  • 31 Jul, 2021
  • +46 other locations
Flexible-Dose Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations (TemPo-3)

The purpose of this study is to assess the effect of tavapadon on the change from baseline in total daily hours of "on" time without troublesome dyskinesia in L-Dopa-treated participants with Parkinson's Disease (PD) who are experiencing motor fluctuations.

Neurosciences Research
 (9.0 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +98 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

teriflunomide
aubagio
evobrutinib
Research Site 715
 (6.7 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +258 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

teriflunomide
hmr1726
contraceptive use
pregnancy test urine
brain lesion
Investigational Site Number 8400011
 (3.6 away) Contact site
  • 0 views
  • 20 Jul, 2021
  • +120 other locations
A Study of Benralizumab in Patients With Eosinophilic Esophagitis

The aim of this Phase 3 study is to investigate the use of benralizumab as a treatment for patients with EoE. The effect of doses of benralizumab on EoE histologic signs and symptoms will be assessed over a 52-week treatment period (including a 24-week double-blind placebo-controlled treatment period and a …

Research Site
 (4.8 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +83 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

teriflunomide
aubagio
evobrutinib
Research Site 649
 (3.6 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +270 other locations