Effingham, Illinois Clinical Trials

A listing of Effingham, Illinois clinical trials actively recruiting patient volunteers.

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Found 78 clinical trials
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

tumor cells
folfiri
solid tumors
rifampin
measurable disease
Crossroads Cancer Center
 (0.9 away) Contact site
  • 65 views
  • 22 Jul, 2021
  • +978 other locations
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery …

tumor cells
lobular carcinoma in situ
lobular carcinoma
hysterectomy
invasive breast cancer
Crossroads Cancer Center
 (0.9 away) Contact site
  • 335 views
  • 21 Jul, 2021
  • +903 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

tumor cells
colony-stimulating factors
interferon
ipilimumab
gm-csf
Carle Physician Group-Mattoon/Charleston
 (26.6 away) Contact site
  • 46 views
  • 09 Jul, 2021
  • +429 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

nausea
treatment regimen
bilateral oophorectomy
diabetes
vomiting
Carle Physician Group-Effingham
 (0.9 away) Contact site
  • 109 views
  • 21 Jul, 2021
  • +595 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

insulin
hysterectomy
measurable disease
replacement therapy
aptt
Carle Physician Group-Mattoon/Charleston
 (26.6 away) Contact site
  • 206 views
  • 15 Jul, 2021
  • +830 other locations
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

This phase II/III trial studies how well daunorubicin and cytarabine with or without uproleselan works in treating older adult patients with acute myeloid leukemia receiving intensive induction chemotherapy. Drugs used in chemotherapy, such as daunorubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by …

leukapheresis
cytarabine
decitabine
hydroxyurea
cytarabine/daunorubicin
Crossroads Cancer Center
 (0.9 away) Contact site
  • 25 views
  • 21 Jul, 2021
  • +103 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

tumor cells
interleukin-2
ipilimumab
measurable disease
metastatic renal cell carcinoma
Crossroads Cancer Center
 (0.9 away) Contact site
  • 157 views
  • 17 Jul, 2021
  • +675 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Crossroads Cancer Center
 (0.9 away) Contact site
  • 85 views
  • 21 Jul, 2021
  • +331 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

colon cancer
tumor cells
hiv viral load
hysterectomy
stage iii colon cancer
Crossroads Cancer Center
 (0.9 away) Contact site
  • 1047 views
  • 21 Jul, 2021
  • +588 other locations
Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

This phase III trial studies how well pembrolizumab works in treating patients with bladder cancer that has spread into the deep muscle of the bladder wall (muscle-invasive) or urothelial cancer that has spread from where it started to nearby tissue or lymph nodes (locally advanced). Monoclonal antibodies recognizing and blocking …

Carle Physician Group-Effingham
 (0.9 away) Contact site
  • 836 views
  • 21 Jul, 2021
  • +755 other locations