Decatur, Illinois Clinical Trials

A listing of Decatur, Illinois clinical trials actively recruiting patient volunteers.

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Found 180 clinical trials
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Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy

This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the …

sentinel lymph node biopsy
taxane
metastatic disease
triple-negative breast cancer
international normalized ratio
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 513 views
  • 24 Jan, 2021
  • +702 other locations
None
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.

intracranial meningioma
step 2
tumor cells
ct scan
central pathology review
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 835 views
  • 22 Sep, 2021
  • +194 other locations
None
Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

This randomized phase II/III trial studies how well giving maintenance chemotherapy with or without local consolidation therapy works in treating patients with stage IV non-small cell lung cancer. Drugs used in maintenance chemotherapy, such as docetaxel, pemetrexed disodium, erlotinib hydrochloride, and gemcitabine work in different ways to stop the growth …

measurable disease
brain metastases
neutrophil count
cancer
tumor cells
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 238 views
  • 26 Sep, 2021
  • +199 other locations
None
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

human immunodeficiency virus
immunosuppressive agents
metastatic disease
squamous cell carcinoma of the head and neck
amylase
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 6053 views
  • 27 Oct, 2021
  • +818 other locations
None
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in treating patients with prostate cancer that has been removed by surgery. Androgen can cause the growth of prostate cells. Antihormone therapy may lessen …

Decatur Memorial Hospital
 (1.5 away) Contact site
  • 1468 views
  • 27 Sep, 2021
  • +339 other locations
None
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

metastatic disease
triple-negative breast cancer
ductal carcinoma in situ
cancer
ductal carcinoma
Cancer Care Center of Decatur
 (1.5 away) Contact site
  • 814 views
  • 24 Jan, 2021
  • +810 other locations
None
Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer

This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued …

primary peritoneal carcinoma
carcinoma
measurable disease
neutrophil count
platinum-based chemotherapy
Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 1729 views
  • 27 Oct, 2021
  • +211 other locations
None
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

mdx-ctla-4
measurable disease
colony-stimulating factors
platelet count
monoclonal antibodies
Cancer Care Specialists of Illinois - Decatur
 (4.8 away) Contact site
  • 46 views
  • 27 Oct, 2021
  • +451 other locations
None
Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery

This randomized phase III trial studies standard or comprehensive radiation therapy in treating patients with early-stage breast cancer who have undergone surgery. Radiation therapy uses high-energy x rays to kill tumor cells. It is not yet known whether comprehensive radiation therapy is more effective than standard radiation therapy in treating …

sentinel lymph node biopsy
taxane
invasive carcinoma
breast cancer staging
ductal carcinoma in situ
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 784 views
  • 10 Oct, 2021
  • +126 other locations
None
Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

This randomized phase II trial studies how well dose-escalated photon intensity-modulated radiation therapy (IMRT) or proton beam radiation therapy works compared with standard-dose radiation therapy when given with temozolomide in patients with newly diagnosed glioblastoma. Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells and …

neutrophil count
contrast-enhanced magnetic resonance imaging
residual tumor
MRI
karnofsky performance status
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 317 views
  • 08 Jul, 2021
  • +44 other locations