Decatur, Illinois Clinical Trials

A listing of Decatur, Illinois clinical trials actively recruiting patient volunteers.

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Found 155 clinical trials
S1803 Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 …

heparin
warfarin
aspirin
lenalidomide
daratumumab
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 90 views
  • 07 Mar, 2021
  • +550 other locations
Testing the Addition of the Drugs Apalutamide and Abiraterone Acetate With Prednisone to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer

This phase III trial studies how well adding apalutamide, abiraterone acetate, and prednisone to the usual hormone therapy and radiation therapy works compared to the usual hormone therapy and radiation therapy in treating patients with node-positive prostate cancer after surgery. Radiation therapy uses high energy x-ray to kill tumor cells …

prostatectomy
endocrine therapy
apalutamide
luteinizing hormone-releasing hormone agonist
tumor cells
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 72 views
  • 09 Jun, 2021
  • +113 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

revlimid
cancer
monoclonal protein
dexamethasone
chemotherapy drugs
Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 0 views
  • 16 Sep, 2021
  • +373 other locations
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug Atezolizumab to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of …

intensity-modulated radiation therapy
oropharyngeal
cancer
cavity
human papillomavirus
Decatur Memorial Hospital
 (4.8 away) Contact site
  • 7 views
  • 15 Sep, 2021
  • +140 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

tubal ligation
ovarian epithelial carcinoma
lung cancer
immunosuppressive therapy
adenocarcinoma
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 6048 views
  • 16 Sep, 2021
  • +817 other locations
A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive Resected Stage II (High Risk) and Stage III Colorectal Cancer

This is a multi-site, open-label, Phase II, randomized, trial to compare the efficacy of RO7198457 versus watchful waiting in patients with circulating tumor DNA (ctDNA) positive, surgically resected Stage II/III rectal cancer, or Stage II (high risk)/Stage III colon cancer.

Cancer Care Center of Decatur, Cancer Care Specialists of IL
 (4.8 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +29 other locations
Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score The PREDICT-RT Trial

This phase III trial compares less intense hormone therapy and radiation therapy to usual hormone therapy and radiation therapy in treating patients with high risk prostate cancer and low gene risk score. This trial also compares more intense hormone therapy and radiation therapy to usual hormone therapy and radiation therapy …

Decatur Memorial Hospital
 (1.5 away) Contact site
  • 0 views
  • 07 Jun, 2021
  • +43 other locations
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted …

Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 0 views
  • 22 Aug, 2021
  • +816 other locations
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 0 views
  • 22 Aug, 2021
  • +283 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 6 views
  • 12 Sep, 2021
  • +368 other locations