Decatur, Illinois Clinical Trials

A listing of Decatur, Illinois clinical trials actively recruiting patient volunteers.

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Found 157 clinical trials
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, …

mitomycin
tubal ligation
pemetrexed
tumor cells
platelet count
Cancer Care Specialists of Illinois - Decatur
 (4.8 away) Contact site
  • 141 views
  • 19 Sep, 2021
  • +590 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 193 views
  • 10 May, 2021
  • +876 other locations
Increasing the Dose of Survivorship Care Planning in Improving Care and Outcomes in Prostate Cancer Survivors Receiving Androgen Deprivation Therapy

This trial studies how well increasing the dose of survivorship care planning improves care and outcomes in prostate cancer survivors receiving radiation therapy and androgen deprivation therapy. There is a need for coordinated care between the cancer care team with the primary care team. This is especially important for prostate …

antiandrogen therapy
androgens
androgen suppression
cancer
diabetes
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 131 views
  • 19 Sep, 2021
  • +67 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

immunodeficiency
pd-l1
pemetrexed
HIV Infection
systemic chemotherapy
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 213 views
  • 19 Sep, 2021
  • +832 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 135 views
  • 16 Sep, 2021
  • +540 other locations
S1803 Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 …

lenalidomide
heparin
warfarin
induction therapy
aspirin
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 90 views
  • 07 Mar, 2021
  • +550 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

progesterone receptor
lumpectomy
estrogen
trastuzumab
mammogram
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 43 views
  • 01 Aug, 2021
  • +576 other locations
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

This phase III trial studies how well the combination of pembrolizumab, paclitaxel and carboplatin works compared with paclitaxel and carboplatin alone in treating patients with endometrial cancer that is stage III or IV, or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

recurrent endometrial cancer
endometrioid adenocarcinoma
MRI
adenocarcinoma
tumor cells
Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 74 views
  • 19 Sep, 2021
  • +190 other locations
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 0 views
  • 22 Aug, 2021
  • +283 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

revlimid
platelet count
plasmacytosis
bone marrow procedure
bortezomib
Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +373 other locations