Decatur, Illinois Clinical Trials

A listing of Decatur, Illinois clinical trials actively recruiting patient volunteers.

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Found 156 clinical trials
S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

This phase III trial studies how well carvedilol works in preventing cardiac toxicity in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. A beta-blocker, such as carvedilol, is used to treat heart failure and high blood pressure, and it …

floctafenine
human epidermal growth factor
other malignancy
electrocardiogram
epidermal growth factor
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 200 views
  • 24 May, 2021
  • +119 other locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued …

primary peritoneal carcinoma
cediranib
pegylated liposomal doxorubicin hydrochloride
bevacizumab
thyroid dysfunction
Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 1729 views
  • 19 Sep, 2021
  • +211 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

nitrosoureas
mdx-ctla-4
interferon
ipilimumab
gilbert's syndrome
Cancer Care Specialists of Illinois - Decatur
 (4.8 away) Contact site
  • 46 views
  • 08 Sep, 2021
  • +436 other locations
Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

This randomized phase II/III trial studies how well giving maintenance chemotherapy with or without local consolidation therapy works in treating patients with stage IV non-small cell lung cancer. Drugs used in maintenance chemotherapy, such as docetaxel, pemetrexed disodium, erlotinib hydrochloride, and gemcitabine work in different ways to stop the growth …

cancer
stage iv non-small cell lung cancer
stereotactic body radiation therapy
brain metastases
measurable disease
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 238 views
  • 06 Jun, 2021
  • +193 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

bone marrow procedure
prednisone
daratumumab
dexamethasone
hypertension
Cancer Care Specialists of Illinois - Decatur
 (1.5 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +373 other locations
Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma

Unity NHL - A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + Umbralisib with or without Bendamustine and Umbralisib alone in Patients with Previously Treated Non-Hodgkin's Lymphoma

hodgkin's disease
large b-cell lymphoma
bendamustine
lymphoma
marginal zone lymphoma
TG Therapeutics Investigational Trial Site
 (1.5 away) Contact site
  • 12 views
  • 01 Sep, 2021
  • +203 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

anaphylactic reactions
antifungal agents
oxaliplatin
hysterectomy
cancer
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 1047 views
  • 19 Sep, 2021
  • +595 other locations
Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo

The main purpose of this study is to learn if the usual chemotherapy given before surgery (neoadjuvant therapy) for breast cancer plus the experimental drug, atezolizumab, is better than the usual chemotherapy plus a placebo. (A placebo is a drug that looks like the study drug but contains no medication.) …

adenocarcinoma of the breast
her2/neu-negative breast cancer
carboplatin
breast cancer
cyclophosphamide
Cancer Care Specialists of Central Illinois
 (1.5 away) Contact site
  • 1000 views
  • 21 Apr, 2021
  • +234 other locations
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.

tumor cells
intracranial meningioma
step 2
x-rays
central pathology review
Decatur Memorial Hospital
 (1.5 away) Contact site
  • 835 views
  • 19 Sep, 2021
  • +190 other locations
A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

This study will test an experimental drug (enfortumab vedotin) alone and with different combinations of anticancer therapies. Pembrolizumab is an immune checkpoint inhibitor (CPI) that is used to treat patients with cancer of the urinary system (urothelial cancer). This type of cancer includes cancer of the bladder, renal pelvis, ureter …

bladder tumor
radical cystectomy
intravesical bcg
transurethral resection
glomerular filtration rate
Decatur Memorial Hospital - Illinois
 (1.5 away) Contact site
  • 284 views
  • 19 Sep, 2021
  • +92 other locations