Centralia, Illinois Clinical Trials

A listing of Centralia, Illinois clinical trials actively recruiting patient volunteers.

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Found 49 clinical trials
Combination Chemotherapy Bevacizumab and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer the COMMIT Study

This phase III trial studies how well combination chemotherapy, bevacizumab, and/or atezolizumab work in treating patients with deficient deoxyribonucleic acid (DNA) mismatch repair colorectal cancer that has spread to other places in the body (metastatic). Chemotherapy drugs, such as fluorouracil, oxaliplatin, and leucovorin calcium, work in different ways to stop …

Carle Physician Group-Effingham
 (51.0 away) Contact site
  • 460 views
  • 24 Sep, 2021
  • +336 other locations
Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

This phase I/II trial studies the side effects and best dose of ipilimumab and nivolumab when given together with brentuximab vedotin, and how well they work in treating patients with Hodgkin lymphoma that has returned after a period of improvement (recurrent) or has not responded to previous treatment (refractory). Immunotherapy …

Centralia Oncology Clinic
 (0.4 away) Contact site
  • 158 views
  • 22 Sep, 2021
  • +370 other locations
Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

This phase III trial studies how well initial treatment with ipilimumab and nivolumab followed by dabrafenib and trametinib works and compares it to initial treatment with dabrafenib and trametinib followed by ipilimumab and nivolumab in treating patients with stage III-IV melanoma that contains a mutation known as BRAFV600 and cannot …

cancer
monoclonal antibodies
absolute neutrophil count
platelet count
ipilimumab
Centralia Oncology Clinic
 (0.4 away) Contact site
  • 426 views
  • 22 Sep, 2021
  • +661 other locations
Testing the Combination of Olaparib and Durvalumab Cediranib and Durvalumab Olaparib and Capivasertib and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone and Olaparib Alone

This phase II trial studies the effects of the combination of olaparib and durvalumab, cediranib and durvalumab, olaparib and capivasertib, and cediranib alone in treating patients with endometrial cancer that has come back (recurrent) or does not respond to treatment (refractory). Olaparib, cediranib, and capivasertib may stop the growth of …

endometrioid adenocarcinoma
x-rays
maintenance therapy
serous adenocarcinoma
endometrial carcinoma
Centralia Oncology Clinic
 (0.4 away) Contact site
  • 81 views
  • 24 Sep, 2021
  • +504 other locations
Testing The Addition of a New Anti-cancer Drug Venetoclax to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated Older Patients With Chronic Lymphocytic Leukemia

This phase III trial compares adding a new anti-cancer drug (venetoclax) to the usual treatment (ibrutinib plus obinutuzumab) in older patients with chronic lymphocytic leukemia who have not received previous treatment. The addition of venetoclax to the usual treatment might prevent chronic lymphocytic leukemia from returning. This trial also will …

night sweats
lymphoid leukemia
cancer
flow cytometry
constitutional symptoms
Centralia Oncology Clinic
 (0.4 away) Contact site
  • 382 views
  • 22 Sep, 2021
  • +740 other locations
A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

This phase II trial studies how pembrolizumab works before and after surgery in treating patients with stage III-IV high-risk melanoma. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.. Giving …

Centralia Oncology Clinic
 (0.4 away) Contact site
  • 71 views
  • 23 Sep, 2021
  • +692 other locations
Inotuzumab Ozogamicin and Blinatumomab in Treating Patients With Newly Diagnosed Recurrent or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

This phase II trial studies how well inotuzumab ozogamicin and blinatumomab work in treating patients with CD22-positive B-lineage acute lymphoblastic leukemia that is newly diagnosed, has come back, or does not respond to treatment. Immunotherapy with monoclonal antibodies, such as inotuzumab ozogamicin and blinatumomab, may help the body's immune system …

Centralia Oncology Clinic
 (0.4 away) Contact site
  • 5 views
  • 22 Sep, 2021
  • +220 other locations
Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. Immunotherapy with antibodies, such as nivolumab and ipilimumab, may remove the brake on the body's …

oophorectomy
cancer
combination therapy
nivolumab
paclitaxel
Centralia Oncology Clinic
 (0.4 away) Contact site
  • 11 views
  • 12 Sep, 2021
  • +288 other locations
NCI COVID-19 in Cancer Patients NCCAPS Study

This study collects blood samples, medical information, and medical images from patients who are being treated for cancer and have a positive test for SARS CoV-2, the new coronavirus that causes the disease called COVID-19. Collecting blood samples, medical information, and medical images may help researchers determine how COVID-19 affects …

cancer
monoclonal antibodies
cancer treatment
HER2
antibody therapy
Cancer Care Center of O'Fallon
 (41.9 away) Contact site
  • 581 views
  • 22 Sep, 2021
  • +733 other locations