Centralia, Illinois Clinical Trials

A listing of Centralia, Illinois clinical trials actively recruiting patient volunteers.

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Found 51 clinical trials
Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors

This phase II trial studies how a diet intervention works in improving bowel dysfunction symptoms related in colon or rectal cancer survivors. Changing a diet may be helpful in reducing the severity of bowel symptoms, including diarrhea and constipation, and improve quality of life in colon or rectal cancer survivors …

low anterior resection
inflammatory bowel disease
cancer
constipation
rectal carcinoma
Centralia Oncology Clinic
 (0.4 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +234 other locations
Docetaxel or Paclitaxel in Reducing Chemotherapy-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

This phase II trial studies how well docetaxel or paclitaxel work in reducing chemotherapy-induced peripheral neuropathy in African American patients with stages I-III breast cancer. Drugs used in chemotherapy, such as docetaxel and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, …

breast carcinoma
cancer
paclitaxel
tumor cells
oophorectomy
Centralia Oncology Clinic
 (0.4 away) Contact site
  • 101 views
  • 27 Sep, 2021
  • +396 other locations
Testing the Addition of an Anti-cancer Drug Pembrolizumab to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

This phase II trial studies the effect of adding pembrolizumab to gemcitabine in treating patients with non-muscle invasive bladder cancer whose cancer does not respond to Bacillus Calmette-Guerin (BCG) treatment. Chemotherapy drugs, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the …

Centralia Oncology Clinic
 (0.4 away) Contact site
  • 60 views
  • 19 Sep, 2021
  • +301 other locations
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer the DECREASE Study

This phase II trial studies how well lower-dose chemotherapy plus radiation (chemoradiation) therapy works in comparison to standard-dose chemoradiation in treating patients with early-stage anal cancer. Drugs used in chemotherapy, such as mitomycin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing …

Cancer Care Center of O'Fallon
 (41.9 away) Contact site
  • 11 views
  • 17 Sep, 2021
  • +372 other locations
A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

This phase II trial studies how pembrolizumab works before and after surgery in treating patients with stage III-IV high-risk melanoma. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.. Giving …

Centralia Oncology Clinic
 (0.4 away) Contact site
  • 71 views
  • 27 Sep, 2021
  • +692 other locations
EA2176: Phase 3 Clinical Trial of Carboplatin and Pacliitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

This phase 3 trial compares the addition of nivolumab to chemotherapy (carboplatin and paclitaxel) versus usual treatment (chemotherapy alone) for the treatment of anal cancer that has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the …

Centralia Oncology Clinic
 (0.4 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +441 other locations
Testing the Addition of Pembrolizumab an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

This phase II trial studies whether adding pembrolizumab to olaparib (standard of care) works better than olaparib alone in treating patients with pancreatic cancer with germline BRCA1 or BRCA2 mutations that has spread to other places in the body (metastatic). BRCA1 and BRCA2 are human genes that produce tumor suppressor …

Centralia Oncology Clinic
 (0.4 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +423 other locations
Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

This phase II trial studies the effect of sacituzumab govitecan in treating patients with HER2-negative breast cancer that has spread to the brain (brain metastases). Sacituzumab govitecan is a monoclonal antibody, called sacituzumab, linked to a chemotherapy drug, called govitecan. Sacituzumab is a form of targeted therapy because it attaches …

Centralia Oncology Clinic
 (0.4 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +169 other locations
Testing The Addition of a New Anti-cancer Drug Venetoclax to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated Older Patients With Chronic Lymphocytic Leukemia

This phase III trial compares adding a new anti-cancer drug (venetoclax) to the usual treatment (ibrutinib plus obinutuzumab) in older patients with chronic lymphocytic leukemia who have not received previous treatment. The addition of venetoclax to the usual treatment might prevent chronic lymphocytic leukemia from returning. This trial also will …

ibrutinib
cancer
gilbert's syndrome
lymphadenopathy
lymphoid leukemia
Centralia Oncology Clinic
 (0.4 away) Contact site
  • 382 views
  • 27 Sep, 2021
  • +740 other locations
Testing the Effects of Early Treatment With Venetoclax and Obinutuzumab Versus Delayed Treatment With Venetoclax and Obinutuzumab for Newly Diagnosed Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Who Do Not Have Symptoms the EVOLVE CLL/SLL Study

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly diagnosed high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma. Venetoclax may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Immunotherapy …

lymphoma
neutrophil count
cancer
monoclonal protein
thrombocytopenia
Centralia Oncology Clinic
 (0.4 away) Contact site
  • 0 views
  • 23 Sep, 2021
  • +384 other locations