Carthage, Illinois Clinical Trials

A listing of Carthage, Illinois clinical trials actively recruiting patient volunteers.

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Found 104 clinical trials
Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation with concomitant and adjuvant …

Illinois CancerCare-Carthage
 (1.9 away) Contact site
  • 167 views
  • 22 Jul, 2021
  • +125 other locations
Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

This randomized phase II trial studies how well ruxolitinib phosphate, and bosutnib, dasatinib, or nilotinib, work in treating patients with chronic myeloid leukemia. Chronic myeloid leukemia cells produce a protein called BCR-ABL. The BCR-ABL protein helps chronic myeloid leukemia cells to grow and divide. Tyrosine kinase inhibitors, such as bosutinib, …

Illinois CancerCare-Carthage
 (1.9 away) Contact site
  • 38 views
  • 11 May, 2021
  • +441 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

metastatic colorectal cancer
adjuvant therapy
irinotecan
bevacizumab
tumor cells
Illinois CancerCare-Carthage
 (1.9 away) Contact site
  • 65 views
  • 22 Jul, 2021
  • +978 other locations
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery …

human chorionic gonadotropin
hysterectomy
hemoglobin a1c
skin carcinoma
invasive breast cancer
Illinois CancerCare-Carthage
 (1.9 away) Contact site
  • 335 views
  • 21 Jul, 2021
  • +903 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

advanced melanoma
nitrosoureas
tumor cells
gm-csf
metastasis
Illinois CancerCare-Macomb
 (24.5 away) Contact site
  • 46 views
  • 09 Jul, 2021
  • +429 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

cyclophosphamide
emetics
metastasis
bilateral oophorectomy
dexamethasone
Illinois CancerCare-Carthage
 (1.9 away) Contact site
  • 109 views
  • 21 Jul, 2021
  • +595 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

hysterectomy
adjuvant therapy
international normalized ratio
immunosuppressive
metastasis
Illinois CancerCare-Macomb
 (24.5 away) Contact site
  • 206 views
  • 15 Jul, 2021
  • +830 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

cabozantinib
metastatic renal cell carcinoma
tremelimumab
tumor cells
metastasis
Illinois CancerCare-Carthage
 (1.9 away) Contact site
  • 157 views
  • 17 Jul, 2021
  • +675 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Illinois CancerCare-Carthage
 (1.9 away) Contact site
  • 85 views
  • 21 Jul, 2021
  • +331 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Illinois CancerCare-Carthage
 (1.9 away) Contact site
  • 193 views
  • 10 May, 2021
  • +876 other locations