Carbondale, Illinois Clinical Trials

A listing of Carbondale, Illinois clinical trials actively recruiting patient volunteers.

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Found 56 clinical trials
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

fluorouracil
irinotecan
open biopsy
cancer
corticosteroids
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 65 views
  • 27 Jul, 2021
  • +978 other locations
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +282 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 27 Jul, 2021
  • +340 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

prednisone
chemotherapy regimen
cancer
daratumumab
lenalidomide
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +365 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

carboplatin
carcinoma
paclitaxel
gemcitabine
platelet count
SIH Cancer Institute
 (7.9 away) Contact site
  • 136 views
  • 01 Aug, 2021
  • +808 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 135 views
  • 01 Aug, 2021
  • +539 other locations
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

This phase III trial compares immunotherapy drugs (nivolumab or brentuximab vedotin) when given with combination chemotherapy in treating patients with newly diagnosed stage III or IV classic Hodgkin lymphoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the …

prednisone
vinblastine
doxorubicin
nivolumab
positron emission tomography/computed tomography
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 68 views
  • 01 Aug, 2021
  • +507 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

ipilimumab
pd-l1
nivolumab
cancer
atezolizumab
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 157 views
  • 01 Aug, 2021
  • +677 other locations
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted …

Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +762 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

luteinizing hormone
vismodegib
dabrafenib
dolutegravir
metastatic cancer
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 6087 views
  • 01 Aug, 2021
  • +1020 other locations