Carbondale, Illinois Clinical Trials

A listing of Carbondale, Illinois clinical trials actively recruiting patient volunteers.

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Found 90 clinical trials
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

irinotecan
metastatic colorectal cancer
vitamin d
tumor cells
major surgery
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 65 views
  • 27 Jul, 2021
  • +978 other locations
A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy

This randomized, placebo-controlled phase III trial is evaluating the benefit of rucaparib and enzalutamide combination therapy versus enzalutamide alone for the treatment of men with prostate cancer that has spread to other places in the body (metastatic) and has become resistant to testosterone-deprivation therapy (castration-resistant). Enzalutamide helps fight prostate cancer …

Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +251 other locations
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted …

Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +762 other locations
Ending Transmission of HIV HCV and STDs and Overdose in Rural Communities of People Who Inject Drugs (ETHIC)

This study will evaluate the referral to harm reduction services (HRS) including syringe services, naloxone overdose prevention, substance use treatment referral, HIV, HCV, and STD testing and referral and linkage to care through capacity building of existing programs through client services data.

venereal disease
substance use
HIV Vaccine
sexually transmitted disease
opioid
Southern Illinois University
 (0.1 away) Contact site
  • 0 views
  • 02 Jul, 2021
  • +1 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

prednisone
bortezomib
bone marrow procedure
chemotherapy drugs
daratumumab
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +365 other locations
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +282 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 0 views
  • 27 Jul, 2021
  • +340 other locations
Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy

This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the …

carcinoma
lobular carcinoma
ductal carcinoma in situ
experimental drug
treatment regimen
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 508 views
  • 24 Jan, 2021
  • +702 other locations
Active Surveillance Bleomycin Carboplatin Etoposide or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. Drugs used in chemotherapy, such as …

carcinoma
human chorionic gonadotropin
tumor cells
neutrophil count
carboplatin
Memorial Hospital of Carbondale
 (7.0 away) Contact site
  • 341 views
  • 30 Jul, 2021
  • +368 other locations
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will …

ischemic attack
transient ischemic attack
carotid revascularization
endarterectomy
angiography
Southern Illinois Healthcare
 (0.5 away) Contact site
  • 1024 views
  • 02 Jun, 2021
  • +147 other locations