Bolingbrook, Illinois Clinical Trials

A listing of Bolingbrook, Illinois clinical trials actively recruiting patient volunteers.

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Found 76 clinical trials
Testing the Combination of Olaparib and Durvalumab Cediranib and Durvalumab Olaparib and Capivasertib and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone and Olaparib Alone

This phase II trial studies the effects of the combination of olaparib and durvalumab, cediranib and durvalumab, olaparib and capivasertib, and cediranib alone in treating patients with endometrial cancer that has come back (recurrent) or does not respond to treatment (refractory). Olaparib, cediranib, and capivasertib may stop the growth of …

cancer
endometrioid adenocarcinoma
x-rays
cytotoxic chemotherapy
cancer chemotherapy
Rush - Copley Medical Center
 (8.9 away) Contact site
  • 81 views
  • 26 Sep, 2021
  • +504 other locations
Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer

This phase II trial studies how well radiation therapy with or without olaparib works in treating patients with inflammatory breast cancer. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for …

olaparib
HER2
axillary lymph node dissection
mammogram
bacterial vaccines
Rush - Copley Medical Center
 (7.8 away) Contact site
  • 54 views
  • 26 Sep, 2021
  • +140 other locations
S1613 Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

This randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified colorectal cancer that has spread from where it started to other places in the body and cannot be removed by surgery. Monoclonal antibodies, such as trastuzumab …

bilateral oophorectomy
cancer
neuropathy
HER2
hormonal therapy
Rush - Copley Medical Center
 (7.8 away) Contact site
  • 428 views
  • 26 Sep, 2021
  • +829 other locations
Trident II Tritanium Acetabular Shell Outcomes Study

The purpose of this study is to review the performance and success rate of an FDA approved cementless hip replacement part called the Trident II Tritanium Acetabular Shell. The study will specifically look at the need to revise the hip replacement after 5 years. This will be compared to how …

arthrosis
joint disease
total hip replacement
osteoarthritis
Hinsdale Orthopaedics
 (8.9 away) Contact site
  • 584 views
  • 19 Sep, 2021
  • +10 other locations
Testing the Addition of the Pill Chemotherapy Cabozantinib to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer

This phase II trial compares cabozantinib alone and the combination of cabozantinib and nivolumab to standard chemotherapy in the treatment of patients with non-squamous non-small cell lung cancer (NSCLC). Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal …

bevacizumab
pd-l1
HIV Infection
hcv viral load
crizotinib
Rush - Copley Medical Center
 (7.8 away) Contact site
  • 25 views
  • 26 Sep, 2021
  • +460 other locations
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

This phase II trial studies how well ramucirumab and paclitaxel or the FOLFIRI regimen (leucovorin calcium, fluorouracil, and irinotecan hydrochloride) work in treating patients with small bowel cancers that have spread extensively to other anatomic sites (advanced) or are no longer responding to treatment (refractory). Ramucirumab is a monoclonal antibody …

Rush - Copley Medical Center
 (7.8 away) Contact site
  • 12 views
  • 27 Sep, 2021
  • +444 other locations
Testing Maintenance Therapy for Small Cell Lung Cancer in Patients With SLFN11 Positive Biomarker

This phase II trial studies whether atezolizumab in combination with talazoparib works better than atezolizumab alone as maintenance therapy for patients with SLFN11-positive extensive-stage small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability …

cancer
maintenance therapy
antiretroviral therapy
HIV Infection
diabetes
Rush - Copley Medical Center
 (7.8 away) Contact site
  • 0 views
  • 25 Sep, 2021
  • +428 other locations
A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes (The INSPIRE Study)

This phase II trial studies the benefit of adding an immunotherapy drug called MEDI4736 (durvalumab) to standard chemotherapy and radiation therapy in treating bladder cancer which has spread to the lymph nodes. Drugs used in standard chemotherapy work in different ways to stop the growth of tumor cells, either by …

cancer
bladder cancer
doxorubicin
HIV Infection
transurethral resection
Rush - Copley Medical Center
 (7.8 away) Contact site
  • 0 views
  • 23 Sep, 2021
  • +157 other locations
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor …

cancer
bevacizumab
doxorubicin
international normalized ratio
fallopian tube
Rush - Copley Medical Center
 (8.9 away) Contact site
  • 185 views
  • 26 Sep, 2021
  • +758 other locations
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. …

cancer
transitional cell carcinoma
liver metastasis
major surgery
cabozantinib
Rush - Copley Medical Center
 (8.9 away) Contact site
  • 191 views
  • 26 Sep, 2021
  • +476 other locations