Bolingbrook, Illinois Clinical Trials

A listing of Bolingbrook, Illinois clinical trials actively recruiting patient volunteers.

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Found 75 clinical trials
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant

The purpose of this study is to assess the efficacy of seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with an selective serotonin reuptake …

Baber Research Group
 (7.6 away) Contact site
  • 13 views
  • 26 Sep, 2021
  • +117 other locations
A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

The purpose of study is to compare bladder intact-event free survival (BI-EFS) in participants receiving TAR-200 in combination with cetrelimab versus concurrent chemoradiotherapy.

radical cystectomy
invasive bladder cancer
neutrophil count
gemcitabine
bladder tumor
DuPage Medical Group
 (6.1 away) Contact site
  • 15 views
  • 23 Sep, 2021
  • +320 other locations
A Study of TAR-200 in Combination With Cetrelimab TAR-200 Alone or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guerin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

The purpose of this study is to evaluate the overall complete response (CR) rate in participants treated with TAR-200 in combination with cetrelimab (Cohort 1), or TAR-200 alone (Cohort 2), or cetrelimab alone (Cohort 3) with Carcinoma in Situ (CIS), with or without concomitant high-grade Ta or T1 papillary disease.

radical cystectomy
cystoscopy
bladder tumor
intravesical bcg
transurethral resection
DuPage Medical Group
 (6.1 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +177 other locations
Randomized Study in Children and Adolescents With Migraine: Acute Treatment

The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.

acute treatment
migraine in children
erenumab
AMR - Baber Research Inc.
 (8.8 away) Contact site
  • 0 views
  • 27 Sep, 2021
  • +109 other locations
A Study of the Change in Disease State and Safety of Oral Cariprazine Capsules in the Treatment of Depression in Pediatric Participants (10 to 17 Years of Age) With Bipolar I Disorder

Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive episodes of bipolar disorder in the pediatric population has not been as widely studied as the treatment of …

mood disorder
depressed mood
depressive episode
Baber Research Group /ID# 232279
 (8.8 away) Contact site
  • 2 views
  • 25 Sep, 2021
  • +66 other locations
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of mirikizumab in participants with moderate-to-severe plaque psoriasis.

mirikizumab
plaque psoriasis
University Dermatology
 (6.3 away) Contact site
  • 727 views
  • 28 Sep, 2021
  • +361 other locations
Testing the Addition of Ixazomib to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma OPTIMUM Trial

This phase III trial studies how well lenalidomide in combination with ixazomib works compared to lenalidomide alone in treating patients with evidence of residual multiple myeloma after stem cell transplantation. Lenalidomide may help shrink or slow the growth of multiple myeloma. Ixazomib may stop the growth of cancer cells by …

chemotherapy regimen
progressive disease
lenalidomide
platelet count
bone marrow procedure
Rush - Copley Medical Center
 (8.9 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +135 other locations
S1613 Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

This randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified colorectal cancer that has spread from where it started to other places in the body and cannot be removed by surgery. Monoclonal antibodies, such as trastuzumab …

brain metastases
other malignancy
endocrine therapy
trastuzumab
metastatic disease
Rush - Copley Medical Center
 (7.8 away) Contact site
  • 428 views
  • 26 Sep, 2021
  • +829 other locations
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor …

bevacizumab
tumor cells
peritoneal cancer
international normalized ratio
atezolizumab
Rush - Copley Medical Center
 (8.9 away) Contact site
  • 185 views
  • 26 Sep, 2021
  • +758 other locations
Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

This phase III trial studies how well initial treatment with ipilimumab and nivolumab followed by dabrafenib and trametinib works and compares it to initial treatment with dabrafenib and trametinib followed by ipilimumab and nivolumab in treating patients with stage III-IV melanoma that contains a mutation known as BRAFV600 and cannot …

tumor cells
ipilimumab
trametinib
lactate dehydrogenase
dabrafenib
Rush - Copley Medical Center
 (8.9 away) Contact site
  • 426 views
  • 27 Sep, 2021
  • +661 other locations