Bolingbrook, Illinois Clinical Trials

A listing of Bolingbrook, Illinois clinical trials actively recruiting patient volunteers.

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Found 77 clinical trials
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

diuretic therapy
stroke
heart disease
nt-probnp
heart failure
Edward Hospital-Main Campus
 (5.2 away) Contact site
  • 16 views
  • 26 Sep, 2021
  • +784 other locations
A Study of TAR-200 in Combination With Cetrelimab TAR-200 Alone or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guerin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

The purpose of this study is to evaluate the overall complete response (CR) rate in participants treated with TAR-200 in combination with cetrelimab (Cohort 1), or TAR-200 alone (Cohort 2), or cetrelimab alone (Cohort 3) with Carcinoma in Situ (CIS), with or without concomitant high-grade Ta or T1 papillary disease.

bladder tumor
invasive bladder cancer
intravesical bcg
transurethral resection
carcinoma
DuPage Medical Group
 (6.1 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +177 other locations
Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 7 to 11 Years With Major Depressive Disorder (MDD)

Investigation of the efficacy and safety of a new potential treatment of Major depressive disorder (MDD) in paediatric patients (age 7 to 11 years)

major depressive disorder
fluoxetine
vortioxetine
US1311
 (5.0 away) Contact site
  • 2 views
  • 26 Sep, 2021
  • +280 other locations
EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis

This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with clinical surveillance (CS) in asymptomatic patients with severe, calcific aortic stenosis.

stenosis
aortic valve replacement
transcatheter aortic valve implantation
ejection fraction
Alexian Brothers Hospital Network
 (6.1 away) Contact site
  • 464 views
  • 16 Sep, 2021
  • +86 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

hepatitis b
ROS1
leptomeningeal disease
squamous non-small cell lung carcinoma
hcv viral load
Edward Hospital/Cancer Center?Plainfield
 (7.4 away) Contact site
  • 213 views
  • 26 Sep, 2021
  • +832 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

atezolizumab
pembrolizumab
cabozantinib
step 2
nivolumab
Edward Hospital/Cancer Center?Plainfield
 (7.4 away) Contact site
  • 157 views
  • 26 Sep, 2021
  • +688 other locations
Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Locally Advanced Pancreatic Cancer

This is a Phase 3, randomized, double-blind trial to evaluate the efficacy and safety of neoadjuvant treatment with pamrevlumab or placebo in combination with either gemcitabine plus nab-paclitaxel (G/NP) or FOLFIRINOX in the treatment of locally advanced, unresectable pancreatic cancer subjects.

Edward Cancer Center
 (5.2 away) Contact site
  • 8 views
  • 26 Sep, 2021
  • +90 other locations
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of mirikizumab in participants with moderate-to-severe plaque psoriasis.

plaque psoriasis
mirikizumab
University Dermatology
 (6.3 away) Contact site
  • 727 views
  • 26 Sep, 2021
  • +361 other locations
A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

The purpose of this study is to assess the efficacy of seltorexant compared with quetiapine extended-release (XR) as adjunctive therapy to an antidepressant drug in treatment response in participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with a selective …

vortioxetine
major depressive disorder
depressive episode
depression
depressive symptoms
Alexian Brothers Health System
 (6.7 away) Contact site
  • 148 views
  • 27 Sep, 2021
  • +180 other locations
Chemoradiation With or Without Atezolizumab in Treating Patients With Limited Stage Small Cell Lung Cancer

This phase III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer. Drugs used in chemotherapy, such as etoposide, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by …

Edward Hospital/Cancer Center?Plainfield
 (7.4 away) Contact site
  • 85 views
  • 27 Sep, 2021
  • +348 other locations