Bolingbrook, Illinois Clinical Trials

A listing of Bolingbrook, Illinois clinical trials actively recruiting patient volunteers.

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Found 76 clinical trials
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body (metastatic). Chemotherapy drugs, such as paclitaxel, work in different ways to stop the growth of tumor cells, either …

platelet count
HER2
liver metastasis
breast cancer
monoclonal antibody therapy
Edward Hospital/Cancer Center?Plainfield
 (7.2 away) Contact site
  • 445 views
  • 26 Sep, 2021
  • +464 other locations
EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis

This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with clinical surveillance (CS) in asymptomatic patients with severe, calcific aortic stenosis.

aortic valve replacement
stenosis
ejection fraction
transcatheter aortic valve implantation
Alexian Brothers Hospital Network
 (6.1 away) Contact site
  • 464 views
  • 16 Sep, 2021
  • +86 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

anticonvulsants
corticosteroids
cardiac disease
pd-l1
insulin
Edward Hospital/Cancer Center?Plainfield
 (7.4 away) Contact site
  • 213 views
  • 26 Sep, 2021
  • +831 other locations
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in treating patients with prostate cancer that has been removed by surgery. Androgen can cause the growth of prostate cells. Antihormone therapy may lessen …

Edward Hospital/Cancer Center
 (5.5 away) Contact site
  • 1468 views
  • 27 Sep, 2021
  • +339 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

ovarian epithelial carcinoma
gilbert's disease
neuroendocrine carcinoma
gilbert's syndrome
immunosuppressive therapy
Rush - Copley Medical Center
 (8.9 away) Contact site
  • 6048 views
  • 26 Sep, 2021
  • +817 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

platelet count
liver metastasis
gilbert's syndrome
monoclonal antibody therapy
measurable disease
Rush - Copley Medical Center
 (7.8 away) Contact site
  • 46 views
  • 26 Sep, 2021
  • +436 other locations
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

This phase III trial compares immunotherapy drugs (nivolumab or brentuximab vedotin) when given with combination chemotherapy in treating patients with newly diagnosed stage III or IV classic Hodgkin lymphoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the …

corticosteroids
topical steroids
positron emission tomography/computed tomography
gilbert's syndrome
alopecia
Rush - Copley Medical Center
 (8.9 away) Contact site
  • 72 views
  • 26 Sep, 2021
  • +511 other locations
A Study of Apalutamide in Participants With High-Risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

The purpose of this study is to determine if treatment with apalutamide plus androgen deprivation therapy (ADT) before and after radical prostatectomy (RP) with pelvic lymph node dissection (pLND) in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rate and …

androgens
prostatectomy
apalutamide
adenocarcinoma of prostate
metastasis
DuPage Medical Group
 (6.1 away) Contact site
  • 318 views
  • 26 Sep, 2021
  • +358 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Rush - Copley Medical Center
 (8.9 away) Contact site
  • 135 views
  • 26 Sep, 2021
  • +539 other locations
Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Locally Advanced Pancreatic Cancer

This is a Phase 3, randomized, double-blind trial to evaluate the efficacy and safety of neoadjuvant treatment with pamrevlumab or placebo in combination with either gemcitabine plus nab-paclitaxel (G/NP) or FOLFIRINOX in the treatment of locally advanced, unresectable pancreatic cancer subjects.

Edward Cancer Center
 (5.2 away) Contact site
  • 8 views
  • 26 Sep, 2021
  • +90 other locations