Alsip, Illinois Clinical Trials

A listing of Alsip, Illinois clinical trials actively recruiting patient volunteers.

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Found 182 clinical trials
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

This phase III trial compares immunotherapy drugs (nivolumab or brentuximab vedotin) when given with combination chemotherapy in treating patients with newly diagnosed stage III or IV classic Hodgkin lymphoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the …

pegfilgrastim
estimated creatinine clearance
combination chemotherapy
hepatitis
cancer
Ingalls Memorial Hospital
 (6.2 away) Contact site
  • 72 views
  • 22 Sep, 2021
  • +511 other locations
A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Late Preterm and Term Infants

The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics (PK), and antidrug antibody (ADA) response for MEDI8897 in healthy late preterm and term infants who are 35 weeks or greater gestational age and entering their first RSV season.

Research Site
 (3.0 away) Contact site
  • 580 views
  • 22 Sep, 2021
  • +414 other locations
A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment

Selexipag is available in many countries for the treatment of pulmonary arterial hypertension (PAH). Due to the similarities between PAH and chronic thromboembolic pulmonary hypertension (CTEPH) and the observed efficacy of other PAH medicines in CTEPH, it is believed that selexipag could benefit to patients with CTEPH. This study aims …

selexipag
endarterectomy
pulmonary arterial hypertension
Advocate Christ Medical Center
 (3.2 away) Contact site
  • 27 views
  • 09 Sep, 2021
  • +288 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

nephrectomy
interleukin-2
cancer
interleukin 2
tumor cells
Ingalls Memorial Hospital
 (6.2 away) Contact site
  • 157 views
  • 22 Sep, 2021
  • +688 other locations
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

This phase III trial studies how well the combination of pembrolizumab, paclitaxel and carboplatin works compared with paclitaxel and carboplatin alone in treating patients with endometrial cancer that is stage III or IV, or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

replacement therapy
serous adenocarcinoma
brachytherapy
cancer
pelvic radiation
University of Chicago Medicine-Orland Park
 (6.3 away) Contact site
  • 74 views
  • 23 Sep, 2021
  • +190 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

replacement therapy
stage iv non-small cell lung cancer
international normalized ratio
hcv viral load
leptomeningeal disease
University of Chicago Medicine-Orland Park
 (5.2 away) Contact site
  • 213 views
  • 22 Sep, 2021
  • +830 other locations
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

This phase II/III trial studies how well daunorubicin and cytarabine with or without uproleselan works in treating older adult patients with acute myeloid leukemia receiving intensive induction chemotherapy. Drugs used in chemotherapy, such as daunorubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by …

cancer
cytarabine
hydroxyurea
acute promyelocytic leukemia
cytarabine/daunorubicin
University of Chicago Medicine-Orland Park
 (6.3 away) Contact site
  • 25 views
  • 22 Sep, 2021
  • +108 other locations
Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

NuTide:121 compares NUC-1031 with gemcitabine, both in combination with cisplatin, in patients with previously untreated advanced biliary tract cancer. The primary hypotheses are: The combination of NUC-1031 plus cisplatin prolongs overall survival compared to the gemcitabine plus cisplatin standard of care The combination of NUC-1031 plus cisplatin increases overall response …

international normalized ratio
platelet count
neutrophil count
measurable disease
renal function
Affiliate Oncologists LLC
 (3.0 away) Contact site
  • 73 views
  • 19 Sep, 2021
  • +129 other locations
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating …

blood transfusion
anticonvulsants
cancer
mri of spine
tumor cells
Advocate Children's Hospital-Oak Lawn
 (3.2 away) Contact site
  • 119 views
  • 03 Sep, 2021
  • +136 other locations
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

The primary objective of this study is to demonstrate the non-inferiority of the vaccine seroresponse to meningococcal serogroups A, C, Y, and W following administration of 2 doses of MenACYW conjugate vaccine compared to 2 doses of MENVEO when given concomitantly with routine pediatric vaccines to infants and toddlers 6 …

Investigational Site Number 8400094
 (8.6 away) Contact site
  • 420 views
  • 20 Jun, 2021
  • +57 other locations