Alsip, Illinois Clinical Trials

A listing of Alsip, Illinois clinical trials actively recruiting patient volunteers.

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Found 182 clinical trials
Safety and Efficacy of SGN-LIV1A Plus Pembrolizumab for Patients With Locally-Advanced or Metastatic Triple-Negative Breast Cancer

This trial studies ladiratuzumab vedotin (LV) with pembrolizumab in patients with triple-negative breast cancer. It will find out what side effects happen when participants get these two drugs. A side effect is anything the drugs do besides treating cancer. Pembrolizumab is a drug that can be used to treat triple-negative …

advanced breast cancer
breast cancer
stage iv breast cancer
cancer
HER2
Ingalls Cancer Care / Ingalls Memorial Hospital
 (6.0 away) Contact site
  • 179 views
  • 23 Aug, 2021
  • +59 other locations
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body (metastatic). Chemotherapy drugs, such as paclitaxel, work in different ways to stop the growth of tumor cells, either …

breast cancer
measurable disease
monoclonal antibodies
pertuzumab
tumor cells
Ingalls Memorial Hospital
 (6.0 away) Contact site
  • 445 views
  • 26 Sep, 2021
  • +464 other locations
An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is a Phase 3, open-label, multicenter extension study to evaluate safety and efficacy of ozanimod in subjects with moderately to severely active Crohn's Disease.

crohn's disease
remission
DM Clinical Research
 (3.5 away) Contact site
  • 1037 views
  • 22 Feb, 2021
  • +807 other locations
A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a Phase 3, randomized, double-blind, placebo-controlled study to demonstrate the effect of oral ozanimod as maintenance therapy in subjects with moderately to severely active Crohn's Disease.

crohn's disease
abdominal pain
remission
DM Clinical Research
 (3.5 away) Contact site
  • 858 views
  • 23 Feb, 2021
  • +780 other locations
A Multicenter Randomized Double-Blind Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2. The objective of Sub-Study 2 is to …

remission
DM Clinical Research/Southwest /ID# 165012
 (3.2 away) Contact site
  • 630 views
  • 26 Sep, 2021
  • +926 other locations
Iobenguane I-131 or Crizotinib and Standard Therapy in Treating Younger Patients With Newly-Diagnosed High-Risk Neuroblastoma or Ganglioneuroblastoma

This phase III trial studies iobenguane I-131 or crizotinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Crizotinib may stop the growth of tumor cells by blocking …

thiotepa
ganglioneuroblastoma
tumor cells
stem cell transplantation
isotretinoin
Advocate Children's Hospital-Oak Lawn
 (3.2 away) Contact site
  • 66 views
  • 03 Sep, 2021
  • +104 other locations
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

This phase III trial studies response-based chemotherapy in treating newly diagnosed acute myeloid leukemia or myelodysplastic syndrome in younger patients with Down syndrome. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by …

bone marrow procedure
transient myeloproliferative disorder
cytopenia
etoposide
cancer
Advocate Children's Hospital-Oak Lawn
 (3.2 away) Contact site
  • 153 views
  • 03 Sep, 2021
  • +141 other locations
Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy

This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the …

epidermal growth factor receptor
tumor cells
treatment regimen
oophorectomy
denosumab
Ingalls Memorial Hospital
 (6.0 away) Contact site
  • 513 views
  • 24 Jan, 2021
  • +702 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

epidermal growth factor receptor
tumor cells
breast adenocarcinoma
pet/ct scan
isolation procedure
Ingalls Memorial Hospital
 (6.0 away) Contact site
  • 814 views
  • 24 Jan, 2021
  • +810 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

adavosertib
adrenaline
pertuzumab
ipatasertib
multiple myeloma
Ingalls Memorial Hospital
 (6.0 away) Contact site
  • 6097 views
  • 26 Sep, 2021
  • +1027 other locations