Kuakini, Hawaii Clinical Trials

A listing of Kuakini, Hawaii clinical trials actively recruiting patient volunteers.

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Found 121 clinical trials
Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

This trial studies the side effects of radiation therapy followed by atezolizumab in treating patients with stage II or III non-small cell lung cancer. Hyperfractionated radiation therapy delivers smaller doses of radiation therapy over time and may kill more tumor cells and have fewer side effects. Immunotherapy with monoclonal antibodies, …

MRI
platelet count
hysterectomy
tumor cells
antiretroviral therapy
Island Urology
 (0.5 away) Contact site
  • 0 views
  • 12 May, 2022
  • +60 other locations
A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

This phase II trial studies how pembrolizumab works before and after surgery in treating patients with stage III-IV high-risk melanoma. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving …

Queen's Medical Center
 (0.5 away) Contact site
  • 82 views
  • 11 May, 2022
  • +620 other locations
Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

This phase I/II trial studies the side effects and best dose of ipilimumab and nivolumab when given together with brentuximab vedotin, and how well they work in treating patients with Hodgkin lymphoma that has returned after a period of improvement (recurrent) or has not responded to previous treatment (refractory). Immunotherapy …

Kaiser Permanente Moanalua Medical Center
 (2.1 away) Contact site
  • 158 views
  • 12 May, 2022
  • +259 other locations
Neuroblastoma Maintenance Therapy Trial (NMTT)

Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter, study for patients with neuroblastoma in remission. In this study subjects will receive 730 Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 ± 250 mg/m2 BID (strata 1, 2, 3, and 4) OR 2500 mg/m2 …

high dose chemotherapy
renal function
bone marrow procedure
eflornithine
tretinoin
Kapiolani Medical Center for Women and Children
 (0.5 away) Contact site
  • 188 views
  • 13 May, 2022
  • +42 other locations
Tazemetostat in Treating Patients With Recurrent Ovarian or Endometrial Cancer

This phase II trial studies how well tazemetostat works in treating patients with ovarian or endometrial cancer that has come back (recurrent). Chemotherapy drugs, such as tazemetostat, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by …

chest x-ray
cancer
tumor cells
hormone therapy
adenocarcinoma
Hawaii Cancer Care Inc - Waterfront Plaza
 (0.9 away) Contact site
  • 87 views
  • 13 May, 2022
  • +431 other locations
Clinical Study Evaluating Efficacy and Safety of T3D-959 in Mild-to-moderate AD Subjects

A Randomized, Double-Blind, Placebo-Controlled Multi-Center Study to Evaluate the Safety and Efficacy of Three Dose Strengths of T3D-959 in Subjects with Mild-to-Moderate Alzheimer's Disease.

mental state examination
dementia
cognitive impairment
mini-mental state examination
neuropsychological test
Hawaii Pacific Neuroscience
 (0.5 away) Contact site
  • 1627 views
  • 14 May, 2022
  • +32 other locations
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

This phase III trial compares whether the addition of pembrolizumab to radiation therapy is more effective than radiation therapy alone in reducing the risk of cancer coming back (recurrence) in patients with newly diagnosed stage I-II endometrial cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

Hawaii Cancer Care Inc - Waterfront Plaza
 (0.9 away) Contact site
  • 1 views
  • 15 May, 2022
  • +172 other locations
Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

This phase II trial studies the effect of adding pembrolizumab to gemcitabine in treating patients with non-muscle invasive bladder cancer whose cancer does not respond to Bacillus Calmette-Guerin (BCG) treatment. Chemotherapy drugs, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the …

Hawaii Cancer Care Inc - Waterfront Plaza
 (0.9 away) Contact site
  • 60 views
  • 11 May, 2022
  • +103 other locations
Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. Immunotherapy with antibodies, such as nivolumab and ipilimumab, may remove the brake on the body's …

immunosuppressive agents
cancer
troponin
combination therapy
tumor cells
Island Urology
 (0.5 away) Contact site
  • 123 views
  • 15 May, 2022
  • +283 other locations
Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma

This phase II/III trial compares the side effects and activity of oral azacitidine in combination with the standard drug therapy (reduced dose rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone [R-miniCHOP]) versus R-miniCHOP alone in treating patients 75 years or older with newly diagnosed diffuse large B cell lymphoma. R-miniCHOP includes a monoclonal …

vincristine
cancer
monoclonal protein
immunoglobulin
diffuse large b-cell lymphoma
Hawaii Cancer Care Inc - Waterfront Plaza
 (0.9 away) Contact site
  • 0 views
  • 15 May, 2022
  • +62 other locations