Kuakini, Hawaii Clinical Trials

A listing of Kuakini, Hawaii clinical trials actively recruiting patient volunteers.

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Found 121 clinical trials
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance. The study will …

Novo Nordisk Investigational Site
 (1.9 away) Contact site
  • 34 views
  • 18 Apr, 2022
  • +168 other locations
An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab (ARTIOS)

Open-label study to evaluate the effectiveness of treatment with ofatumumab in subjects transitioning from any fumarate-based RMS approved therapy or fingolimod due to breakthrough disease.

dimethyl fumarate
ofatumumab
fingolimod
Novartis Investigative Site
 (1.8 away) Contact site
  • 183 views
  • 14 May, 2022
  • +135 other locations
A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity. (DIRECTION)

This study is aiming to demonstrate the non-inferiority of AbobotulinumtoxinA (aboBoNT-A) versus OnabotulinumtoxinA (onaBoNT-A) as the primary safety endpoint, and the superiority of aboBoNT-A over onaBoNT-A with respect to duration of response as the key secondary efficacy endpoint when used at optimal doses according to approved prescribing information of each …

Hawaii Pacific Neuroscience
 (0.5 away) Contact site
  • 0 views
  • 10 May, 2022
  • +33 other locations
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer

This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.

Queen's Medical Center
 (0.5 away) Contact site
  • 2663 views
  • 03 May, 2022
  • +76 other locations
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis

Novartis Investigative Site
 (1.9 away) Contact site
  • 0 views
  • 10 May, 2022
  • +9 other locations
COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis

A multicenter, adaptive, randomized platform trial evaluating the efficacy and safety of antithrombotic strategies in patients with COVID-19 following hospital discharge

Hawaii Pacific Health
 (0.5 away) Contact site
  • 40 views
  • 10 May, 2022
  • +115 other locations
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

This study will be conducted to evaluate the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) compared to placebo for the treatment of agitation in participants with dementia of the Alzheimer's type.

Clinical Research Site
 (1.8 away) Contact site
  • 0 views
  • 10 May, 2022
  • +55 other locations
PROACTIVE-HF IDE Trial Heart Failure NYHA Class III (PROACTIVE-HF)

This is a prospective, open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart Failure Patients compared to a Performance Goal (PG).

Queens Medical Center
 (0.5 away) Contact site
  • 59 views
  • 08 Apr, 2022
  • +53 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer (SOLARIS)

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

fluorouracil
metastatic colorectal cancer
cancer treatment
neutrophil count
oxaliplatin
Island Urology
 (0.5 away) Contact site
  • 140 views
  • 30 Apr, 2022
  • +922 other locations
REperfusion With Cooling in CerebraL Acute IscheMia II (RECCLAIM-II)

The primary objective of this study is to determine the feasibility and safety of achieving rapid hypothermia with the Proteus Intravascular Temperature Management (IVTM) system for patients experiencing acute ischemic stroke due to a large vessel occlusion.

thrombectomy
angiography
hypothermia
ischemia
stroke
The Queen's Medical Center
 (0.5 away) Contact site
  • 21 views
  • 12 May, 2022
  • +6 other locations