Trinity, Florida Clinical Trials

A listing of Trinity, Florida clinical trials actively recruiting patient volunteers.

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Found 83 clinical trials
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study designed to confirm the benefits of mepolizumab treatment on moderate or severe exacerbations in COPD participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 57 weeks, consisting of 2 …

fluticasone
antibiotics
copd exacerbation
corticosteroids
albuterol
GSK Investigational Site
 (3.8 away) Contact site
  • 379 views
  • 15 Apr, 2021
  • +204 other locations
A Research Study to Compare a New Weekly Insulin Insulin Icodec Used With DoseGuide App and Daily Insulins in People With Type 2 Diabetes Who Have Not Used Insulin Before

This study compares insulin icodec to different daily insulins in people with type 2 diabetes. The study will look at how well insulin icodec taken once weekly controls blood sugar compared to the insulins taken once daily. Participants will either get insulin icodec, that participants will have to inject once …

Novo Nordisk Investigational Site
 (4.7 away) Contact site
  • 0 views
  • 02 Jun, 2021
  • +140 other locations
A Study of Sodium Oligomannate (GV-971) in Participants With Mild to Moderate Alzheimer's Disease

The purpose of this study is to evaluate the safety, tolerability and efficacy of GV-971 in mild to moderate Alzheimer's disease.

Suncoast Clinical Research Inc. / Site 1120
 (5.4 away) Contact site
  • 0 views
  • 29 Apr, 2021
  • +6 other locations
Study to Gather Information How Well Three Different Doses of BAY1817080 Given Twice Daily Over 12 Weeks Work in Comparison to an Inactive Pill (Placebo) and Elagolix in Women Suffering From Pain Related to a Condition Where the Tissue That Usually Grows Inside the Womb Grows Outside of the Womb

The purpose of this study is to assess safety and efficacy of BAY1817080 compared to elagolix and placebo in women with symptomatic endometriosis. Study details include: Study duration: 155 up to 285 days Treatment duration: 84 days Visit frequency: approximately once a month

analgesic
elagolix
laparotomy
ibuprofen
laparoscopy
Suncoast Clinical Research Center, Inc.
 (4.7 away) Contact site
  • 0 views
  • 03 Jun, 2021
  • +201 other locations
Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD)

Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. This study will evaluate how well risankizumab works compared to ustekinumab. This study will assess change in Crohn's Disease Activity Index (CDAI). Risankizumab is an investigational drug being developed for the treatment of …

crohn's disease
tumor necrosis factor
ustekinumab
risankizumab
abdominal pain
Advanced Research Institute /ID# 223470
 (3.8 away) Contact site
  • 97 views
  • 14 Jun, 2021
  • +383 other locations
A Study of the Efficacy and Safety of Upadacitnib (ABT-494) in Participants With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Conventional and/or Biologic Therapies

The objective of this study is to evaluate the efficacy and safety of upadacitinib compared to placebo as induction therapy in participants with moderately and severely active Crohn's disease (CD).

corticosteroids
abdominal pain
conventional treatment
mucosal inflammation
crohn's disease
Advanced Research Institute /ID# 164921
 (4.5 away) Contact site
  • 824 views
  • 02 Jun, 2021
  • +730 other locations
Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS) Chronic Myelomonocytic Leukemia (CMML) or Low-Blast Acute Myelogenous Leukemia (AML)

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared with single-agent azacitidine. (An event is defined as death or transformation to AML in participants with MDS or CMML, whichever occurs first, and is defined as death in participants …

myelodysplastic syndromes
chronic myelomonocytic leukemia
azacitidine
myeloid leukemia
pevonedistat
SCRI Florida Cancer Specialists North
 (2.2 away) Contact site
  • 341 views
  • 13 Jun, 2021
  • +319 other locations
Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC

This study compares rPFS in men with mCRPC treated with talazoparib plus enzalutamide vs. enzalutamide after confirmation of the starting dose of talazoparib in combination with enzalutamide.

Florida Cancer Specialists
 (2.2 away) Contact site
  • 4293 views
  • 27 May, 2021
  • +497 other locations
Evaluation of the Long Term Safety Tolerability and Efficacy of Two Dosing Regimens of Olokizumab (OKZ) in Subjects With Rheumatoid Arthritis (RA) Who Previously Completed 24 Weeks of Blinded Treatment in One of the Core Studies - CREDO 1 2 or 3.

The purpose of the study is to evaluate how safe, how effective and how well tolerated, the study drug Olokizumab is, in the long-term, in patients with Rheumatoid Arthritis (RA) who have previously taken part in and completed 24 weeks of blinded treatment in one of the core studies - …

folic acid
folate
methotrexate
Suncoast Clinical Research Inc.
 (4.7 away) Contact site
  • 806 views
  • 22 Jan, 2021
  • +295 other locations
A Safety Extension Study of Ontamalimab in Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease (AIDA)

The purpose of this study is to evaluate the safety and tolerability of long-term treatment with ontamalimab in participants with moderate to severe Ulcerative Colitis (UC) or Crohn's disease (CD).

ulcerative colitis
ulcerative colitis or crohn's
hematochezia
sigmoidoscopy or colonoscopy
vedolizumab
Bayside Clinical Research
 (2.2 away) Contact site
  • 1349 views
  • 15 Jun, 2021
  • +824 other locations