Trinity, Florida Clinical Trials

A listing of Trinity, Florida clinical trials actively recruiting patient volunteers.

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Found 89 clinical trials
A 12 Month Site Randomized Trial in Adults With Type 2 Diabetes Mellitus and History of Cardiovascular Disease

COORDINATE-Diabetes is a cluster-randomized clinical trial to test the effectiveness of an innovative, clinic-level educational intervention to improve the management of patients with type 2 diabetes mellitus and cardiovascular disease.

stenosis
diabetes
cardiovascular disease
coronary artery bypass graft
peripheral artery disease
Interventional Cardiac Consultants
 (2.2 away) Contact site
  • 182 views
  • 15 Mar, 2021
  • +50 other locations
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study designed to confirm the benefits of mepolizumab treatment on moderate or severe exacerbations in COPD participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 57 weeks, consisting of 2 …

eosinophil count
corticosteroids
copd exacerbation
muscarinic antagonists
albuterol
GSK Investigational Site
 (3.8 away) Contact site
  • 379 views
  • 24 Jul, 2021
  • +232 other locations
Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

The GLORIA study is a Phase III, randomized, open-label study to prospectively evaluate the efficacy and safety of adagloxad simolenin (OBI 822)/OBI-821 in the adjuvant treatment of patients with high risk, early stage Globo-H Positive TNBC.

taxane
estrogen
serum total bilirubin
adjuvant chemotherapy
renal function test
Advanced Research Institute, Inc.
 (4.5 away) Contact site
  • 309 views
  • 10 May, 2021
  • +125 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

semaglutide
chronic disease
stroke
Novo Nordisk Investigational Site
 (4.7 away) Contact site
  • 1276 views
  • 05 Aug, 2021
  • +557 other locations
An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

This is an open-label, multicenter, non-randomized, Phase 2 study to determine the safety, tolerability and efficacy of encorafenib given in combination with binimetinib in patients with BRAFV600E-mutant metastatic non-small cell lung cancer (NSCLC). Patients who are either treatment-nave, OR who have received 1) first-line treatment with standard platinum-based chemotherapy, OR …

secondary malignant neoplasm of liver
platinum-based chemotherapy
neutrophil count
lung carcinoma
measurable disease
Florida Cancer Specialist
 (4.9 away) Contact site
  • 3 views
  • 21 Jul, 2021
  • +292 other locations
Efficacy & Safety of TD-1473 in Ulcerative Colitis

A Phase 2b/3 set of studies to evaluate the efficacy and safety of induction and maintenance therapy with TD-1473 in subjects with moderately-to-severely active ulcerative colitis with up to 60 weeks of treatment.

aminosalicylates
immunomodulators
corticosteroids
Theravance Biopharma Investigational Site
 (4.5 away) Contact site
  • 75 views
  • 28 Jan, 2021
  • +202 other locations
A DOSE-RANGING STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-06700841 IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Assessment of PF-06700841 in participants with moderate to severe active, generalized Systemic Lupus Erythematosus (SLE) that have inadequate response to standard of care.

azathioprine
mycophenolate
antimalarials
corticosteroids
lupus
Akumin, Inc
 (5.9 away) Contact site
  • 198 views
  • 05 Aug, 2021
  • +224 other locations
Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs)

This study [contRAst 2 (201791: NCT03970837)] is a phase 3, randomized, multicenter, double blind study to assess the safety and efficacy of GSK3196165 in combination with csDMARD(s), for the treatment of adult participants with moderate to severe active rheumatoid arthritis (RA) who have had an inadequate response to csDMARD(s) or …

chloroquine
DMARD
arthralgia
tofacitinib
hydroxychloroquine
GSK Investigational Site
 (4.7 away) Contact site
  • 302 views
  • 14 May, 2021
  • +223 other locations
A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis

This is a Phase 1b/2, multi-center study in which patients will receive KZR-616, administered as a subcutaneous (SC) injection weekly for 13 weeks (Phase 1b) or 24 weeks (Phase 2).

adrenaline
corticosteroids
lupus
mycophenolic acid
hydroxychloroquine
KZR Research Site
 (7.1 away) Contact site
  • 261 views
  • 10 May, 2021
  • +38 other locations
An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is a Phase 3, open-label, multicenter extension study to evaluate safety and efficacy of ozanimod in subjects with moderately to severely active Crohn's Disease.

remission
crohn's disease
Bayside Clinical Research
 (2.2 away) Contact site
  • 1035 views
  • 22 Feb, 2021
  • +807 other locations