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South Miami, Florida Clinical Trials

A listing of South Miami, Florida clinical trials actively recruiting patient volunteers.

RESULTS

Found (38) clinical trials

Radiation Hypofractionation Via Extended Versus Accelerated Therapy (HEAT) For Prostate Cancer

Accelerated Hypofractionation Radiotherapy for prostate cancer of 36.25 Gy delivered in 5 fractions will not be inferior to the standard treatment of 70.2 Gy given in 26 fractions with respect to two-year failure defined as a positive biopsy two years post treatment completion or earlier evidence of biochemical or clinical ...

Phase N/A

7.78 miles

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A Study to Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study)

The primary purpose of this study is to describe the time to tolerization (i.e., ITI success) with rFVIIIFc in participants within a maximum of 48 weeks (12 months) of ITI treatment.

Phase

7.78 miles

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Dose-Ranging Study of Recombinant AAV2/6 Human Factor 8 Gene Therapy SB-525 in Subjects With Severe Hemophilia A

The objective of the study is to reduce or eliminate the need for FVIII replacement therapy. The proposed SB-525 clinical study uses a recombinant adeno-associated virus 2/6 (AAV2/6) vector encoding the cDNA for the B-domain deleted human F8 (hF8). The secreted FVIII has the same amino acid sequence as approved ...

Phase

7.78 miles

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A Unified Intervention for Young Gay and Bisexual Men's Minority Stress Mental Health and HIV Risk

ESTEEM (Effective Skills to Empower Effective Men) is a 10-session skills-building intervention designed to reduce young gay and bisexual men's (YGBM) co-occurring health risks by reducing the underlying cognitive, affective, and behavioral pathways through which minority stress impairs YGBM's health. ESTEEM is based on the Unified Protocol, a cognitive-behavioral therapy ...

Phase N/A

7.78 miles

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Collection and Measurement of Biomarkers in Prostate Cancer Radiotherapy Patients

Treatment: Prostatectomy, radiotherapy technique, radiotherapy dose, and the use of androgen deprivation therapy (ADT), are per the standard of care at the University of Miami, and are not specified in this protocol. Measurements: Prior to treatment and at 3 months, 6 months, and at 2.0-2.5 years after treatment, the patients ...

Phase N/A

7.78 miles

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Randomized MRI-Guided Prostate Boosts Via Initial Lattice Stereotactic vs Daily Moderately Hypofractionated Radiotherapy

Radiotherapy (RT) is a commonly applied primary (initial definitive) treatment alternative to prostatectomy that allows for preservation of anatomy and the potential for improved functional outcome with better tumor targeting and normal tissue sparing. About 30-50% of men ultimately develop biochemical failure (BF) after RT, depending on risk factors. Persistence ...

Phase N/A

7.78 miles

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The Miami MAST Trial

Single arm therapeutic trial investigating the impact of MRI and MRI-US fusion biopsy to identify higher grade or volume tumors early on for better selection of patients for active surveillance and improved outcomes for those undergoing delayed treatment after initial observation.. MRI-US fusion biopsy will include targeting of suspicious areas ...

Phase N/A

7.78 miles

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Natural History of the Progression of Choroideremia Study

Choroideremia (CHM) is a rare, X-linked recessive, degenerative disease of the retina which begins in childhood with loss of night vision and gradually progresses to legal blindness by the fifth decade. There are no approved treatements for CHM and the disease is poorly characterised given its rare nature and scarscity ...

Phase N/A

7.78 miles

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A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients Without Inhibitors

The purpose of this study is to determine the frequency of bleeding episodes in patients receiving fitusiran as prophylactic treatment of hemophilia compared with patients who are assigned to continue with their regular medication. In addition, the study will assess safety, quality of life, pharmacodynamics (PD), and pharmacokinetics (PK).

Phase

7.78 miles

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A Safety Study of Retinal Gene Therapy for Choroideremia

This is a phase 2 clinical trial of a gene therapy vector made from adenoassociated virus (AAV) called AAV2-REP1 for the treatment of Choroideremia. Participating subjects will be required to attend a screening visit during which their suitability for the study will be assessed, and eligible subjects will undergo a ...

Phase

7.78 miles

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