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North Miami, Florida Clinical Trials

A listing of North Miami, Florida clinical trials actively recruiting patient volunteers.

RESULTS

Found (10) clinical trials

An Efficacy and Safety Study of Lanabecestat (LY3314814) in Early Alzheimer's Disease

Participants who meet other study entry requirements will be required to undergo either an amyloid positron emission tomography (PET) scan or a lumbar puncture for cerebrospinal fluid (CSF) sampling at screening to document presence of abnormal levels of brain and CSF amyloid for study inclusion. The study includes 2 sub-studies: ...

Phase

5.15 miles

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Safety Tolerability and Pharmacokinetics of MK-1654 in Infants (MK-1654-002)

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and incidence of anti-drug antibodies (ADAs) of single ascending doses of MK-1654 in healthy pre-term (born at 29 to 35 weeks gestational age) and full-term (born at >35 weeks gestational age) infants. Key safety and tolerability variables will ...

Phase

6.03 miles

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BTRX-246040 Study in Subjects With Parkinson's Disease With Motor Fluctuations

Study treatment is 1 day and total duration of the study is up to 36 days, including an approximate 28-day screening period. The study will consist of 4 sequential, ascending dose cohorts of 8 subjects each with a 6:2 randomization to BTRX-246040 or placebo. The planned dosing for each cohort ...

Phase

7.15 miles

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Early Detection of Progressive Kidney Disease in Preterm Infants

Objectives and Hypotheses: Infants born preterm and of low birth weight are known to be at increased risk for early onset of cardiovascular and renal disease in later life. This has been related to low nephron mass due to inadequate or early termination of glomerulogenesis in utero and during the ...

Phase N/A

7.25 miles

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A Study to Assess the Safety Tolerability and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

The primary objective of this study is to evaluate the safety and tolerability of BIIB078 in adults with C9ORF72-ALS. The secondary objective of this study is to evaluate the pharmacokinetic profile of BIIB078.

Phase

7.25 miles

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Combination Pembrolizumab Chemotherapy and Bevacizumab in Patients With Cervical Cancer

This is a single arm, open-label, phase II study to assess progression free survival in patients treated with pembrolizumab, chemotherapy, and bevacizumab for recurrent, persistent, or metastatic cervical cancer. Progression free survival will be assessed in patients treated with this combination. Eligible patients will require tissue biopsy for diagnostic confirmation ...

Phase

7.25 miles

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A Multicenter Clinical Trial to Evaluate the Effectiveness of Intermittent Hypoxia Therapy in Individual With Spinal Cord Injury

The overall objective of this project is to investigate the effectiveness of daily acute intermittent hypoxia therapy (dAIH), coupled with massed practice training, to improve upper-extremity function in individuals with chronic incomplete cervical spinal cord injury (SCI).

Phase N/A

7.25 miles

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A Study to Evaluate the Efficacy and Safety of Gefapixant (MK-7264) in Women With Endometriosis-Related Pain (MK-7264-034)

The purpose of this study is to evaluate the efficacy, safety, and tolerability of gefapixant (MK-7264) in premenopausal female participants with moderate to severe endometriosis-related pain. The primary hypothesis: gefapixant is superior to placebo in reducing the average daily pelvic pain score (cyclic and non-cyclic) during Treatment Cycle 2.

Phase

7.45 miles

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Evaluation of SPN-812 ER Low Dose in Children With ADHD

This is a multicenter, randomized, double-blind, placebo-controlled, 3-arm, parallel-group study, to assess the efficacy and safety of SPN-812 ER as monotherapy for the treatment of children 6-11 years old with ADHD.

Phase

7.6 miles

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Evaluating the Efficacy and Safety of BG00011 in Participants With Idiopathic Pulmonary Fibrosis

The primary objective of this study is to evaluate the efficacy of BG00011 compared with placebo in participants with Idiopathic Pulmonary Fibrosis (IPF). The secondary objectives of this study are: to evaluate the efficacy of BG00011 compared with placebo in participants with IPF as determined by change in percent predicted ...

Phase

8.0 miles

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