Bradenton, Florida Clinical Trials

A listing of Bradenton, Florida clinical trials actively recruiting patient volunteers.

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Found 51 clinical trials
A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Patients With Metastatic Colorectal Cancer

This is a global, randomized, double-blind, placebo-controlled, multicenter phase 3 clinical trial to compare the efficacy and safety of fruquintinib plus best supportive care (BSC) versus placebo plus BSC in patients with refractory metastatic colorectal cancer (mCRC). 687 subjects will be randomized to one of the following treatment arms in …

irinotecan
measurable disease
cancer
tipiracil
vegf
Florida Cancer Specialists South
 (6.7 away) Contact site
  • 0 views
  • 30 Apr, 2021
  • +138 other locations
A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

Sarasota Clinical Research
 (7.1 away) Contact site
  • 17 views
  • 20 Jun, 2021
  • +108 other locations
Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

Endometriosis is a painful disorder of the uterus affecting 6-10% of women of childbearing age. Endometriosis affects daily activities, social relationships, sexuality and sexual activity, and mental health. This study will evaluate how well elagolix in combination with combined oral contraceptives (COC) works within the body and/or how safe it …

elagolix
dysmenorrhea
endometriosis
combined oral contraceptives
Physician Care Clin. Res., LLC /ID# 217264
 (7.4 away) Contact site
  • 392 views
  • 20 Jun, 2021
  • +195 other locations
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

The objectives of this study are to evaluate the safety and efficacy of Zimura intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)

geographic atrophy
age-related macular degeneration
complement c5
macular degeneration
atrophy
Retina Associates of Sarasota
 (8.1 away) Contact site
  • 318 views
  • 19 Jun, 2021
  • +204 other locations
Phase 3 Study of ProstAtak Immunotherapy With Standard Radiation Therapy for Localized Prostate Cancer

The purpose of this study is to evaluate the effectiveness of ProstAtak immunotherapy in combination with radiation therapy for patients with intermediate-high risk localized prostate cancer. ProstAtak kills tumor cells and stimulates a cancer vaccine effect. Killing tumor cells in an immune stimulatory environment induces the body's immune system to …

androgens
antiandrogen therapy
androgen suppression
cancer vaccine
tumor cells
21st Century Oncology
 (2.6 away) Contact site
  • 1420 views
  • 02 Jun, 2021
  • +78 other locations
AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

Objectives Primary: To test the hypothesis that apixaban is superior to aspirin for the prevention of recurrent stroke in patients with cryptogenic ischemic stroke and atrial cardiopathy. Secondary: To test the hypothesis that the relative efficacy of apixaban over aspirin increases with the severity of atrial cardiopathy.

recurrent strokes
brain imaging
infarct
aspirin
heart disease
Sarasota Memorial
 (7.4 away) Contact site
  • 378 views
  • 26 Jan, 2021
  • +174 other locations
Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC

This study compares rPFS in men with mCRPC treated with talazoparib plus enzalutamide vs. enzalutamide after confirmation of the starting dose of talazoparib in combination with enzalutamide.

Florida Cancer Specialists
 (5.4 away) Contact site
  • 4293 views
  • 27 May, 2021
  • +497 other locations
A Study of the Efficacy and Safety of Upadacitnib (ABT-494) in Participants With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Conventional and/or Biologic Therapies

The objective of this study is to evaluate the efficacy and safety of upadacitinib compared to placebo as induction therapy in participants with moderately and severely active Crohn's disease (CD).

immunosuppressive agents
abdominal pain
conventional treatment
crohn's disease
endoscopy
Florida Research Institute /ID# 211601
 (2.6 away) Contact site
  • 824 views
  • 02 Jun, 2021
  • +730 other locations
Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS) Chronic Myelomonocytic Leukemia (CMML) or Low-Blast Acute Myelogenous Leukemia (AML)

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared with single-agent azacitidine. (An event is defined as death or transformation to AML in participants with MDS or CMML, whichever occurs first, and is defined as death in participants …

myelomonocytic leukemia
myeloid leukemia
blast cells
induction chemotherapy
myelodysplastic syndromes
SCRI Florida Cancer Specialists South
 (7.0 away) Contact site
  • 341 views
  • 20 Jun, 2021
  • +319 other locations
Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

The purpose of this study is to assess the efficacy and safety of treatment with carboplatin/paclitaxel* PLUS pembrolizumab (MK-3475) and maintenance olaparib (MK-7339) in women with epithelial ovarian cancer (EOC), fallopian tube cancer, or primary peritoneal cancer. The primary study hypotheses are that the combination of pembrolizumab plus carboplatin/paclitaxel* followed …

solid tumors
paclitaxel
mk-3475
cancer
fallopian tube
Sarasota Memorial Hospital ( Site 0023)
 (7.1 away) Contact site
  • 732 views
  • 20 Jun, 2021
  • +261 other locations