Bradenton, Florida Clinical Trials

A listing of Bradenton, Florida clinical trials actively recruiting patient volunteers.

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Found 52 clinical trials
Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab

The purpose of this extension study is to establish efficacy and safety of ligelizumab. This will be assessed in adult and adolescent chronic spontaneous urticaria (CSU) patients who have completed a preceding ligelizumab study and have relapsed, following treatment in these preceding studies, despite standard of care H1-antihistamine (H1-AH) treatment. …

ligelizumab
urticaria
antihistamines
Novartis Investigative Site
 (3.7 away) Contact site
  • 0 views
  • 15 Jun, 2021
  • +215 other locations
Randomized Double-blind Efficacy and Safety Study of Doravirine/Islatravir (DOR/ISL) in Treatment-na ve Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-020)

This is a phase 3, randomized, controlled, double-blind clinical study of a once-daily fixed dose combination (FDC) of 100 mg doravirine/0.75 mg islatravir (DOR/ISL [also known as MK-8591A]) in treatment-nave participants with human immunodeficiency virus type-1 (HIV-1) infection. The primary hypothesis is that DOR/ISL is non-inferior to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) …

CAN Community Health ( Site 5627)
 (5.0 away) Contact site
  • 4 views
  • 13 Jun, 2021
  • +66 other locations
Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS) Chronic Myelomonocytic Leukemia (CMML) or Low-Blast Acute Myelogenous Leukemia (AML)

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared with single-agent azacitidine. (An event is defined as death or transformation to AML in participants with MDS or CMML, whichever occurs first, and is defined as death in participants …

myelodysplastic syndromes
azacitidine
myeloid leukemia
blast cells
leukemia
SCRI Florida Cancer Specialists South
 (7.0 away) Contact site
  • 341 views
  • 17 Jun, 2021
  • +319 other locations
Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria at …

crohn's disease
vedolizumab
corticosteroids
maintenance treatment
tumor necrosis factor alpha
Florida Research Institute
 (6.5 away) Contact site
  • 0 views
  • 31 May, 2021
  • +550 other locations
A Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

The reason for this study is to see if the study drug mirikizumab is safe and effective in participants with moderately to severely active Crohn's disease.

crohn's disease
ustekinumab
Florida Research Institute
 (2.6 away) Contact site
  • 646 views
  • 16 Jun, 2021
  • +976 other locations
Comparing the Efficacy and Safety of Biosimilar Candidate Xlucane Versus Lucentis in Patients With nAMD

The objectives of the study are to demonstrate the equivalence of Xlucane to Lucentis in treatment of subjects with wet (ie, neovascular) age-related macular degeneration (wAMD).

vegf
vascular endothelial growth factor
fluorescein angiography
bevacizumab
neovascularization
Sarasota Retina Institute
 (7.4 away) Contact site
  • 249 views
  • 24 Jan, 2021
  • +108 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

stroke
myocardial infarction
diabetes
arterial disease
infarct
Intercoastal Medical Group
 (5.4 away) Contact site
  • 536 views
  • 14 Jun, 2021
  • +1330 other locations
Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Relief of CeD Symptoms

To assess the efficacy and safety of larazotide acetate versus placebo for the relief of persistent symptoms in adult celiac disease patients.

larazotide
bloating
serologic test
gluten
diarrhea
Research Site
 (2.6 away) Contact site
  • 823 views
  • 21 Apr, 2021
  • +203 other locations
Fenofibrate for Prevention of DR Worsening

This randomized trial will evaluate the effect of fenofibrate compared with placebo for prevention of diabetic retinopathy (DR) worsening through 4 years of follow-up in participants with mild to moderately severe non-proliferative DR (NPDR) and no CI-DME at baseline. In addition to evaluating efficacy, this study aims to evaluate the …

pupil dilation
insulin
microaneurysms
diabetes
severe nonproliferative diabetic retinopathy
Sarasota Retina Institute
 (7.1 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +9 other locations
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance. The study will …

Novo Nordisk Investigational Site
 (7.1 away) Contact site
  • 0 views
  • 17 Jun, 2021
  • +80 other locations