Littleton, Colorado Clinical Trials

A listing of Littleton, Colorado clinical trials actively recruiting patient volunteers.

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Found 298 clinical trials
Interventional, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Delayed-Start Study to Evaluate the Efficacy and Safety of Eptinezumab in Patients With Episodic Cluster Headache (ALLEVIATE)

The purpose of this study is to evaluate the efficacy of eptinezumab in participants with episodic Cluster Headache (eCH)

Neurology Colorado - Denver Advanced Neurological Evaluation and Treatment Center
 (8.6 away) Contact site
  • 1 views
  • 20 Sep, 2022
  • +104 other locations
A Randomized, Double-Blind, Placebo-Controlled Study in Cat-Allergic Patients With Allergic Rhinitis Who Live With a Cat to Assess the Efficacy and Safety of Anti-Fel d 1 Antibodies During Natural Cat Exposure in the Home

The primary objective of the study is to determine the efficacy of REGN1908-1909, as compared to placebo, to reduce allergic rhinitis/conjunctivitis symptoms and allergy rescue medication use during natural cat exposure. The Secondary Objectives are: To assess the reduction of allergic symptoms and use of allergy rescue medications after treatment …

Colorado Allergy and Asthma Centers PC - CRN - PPDS
 (9.9 away) Contact site
  • 3 views
  • 20 Sep, 2022
  • +90 other locations
A Multi-Center, Multi-National, Randomized, Double-Blind, Placebo-Controlled Induction and Long-term Controlled Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Subjects With Active Eosinophilic Esophagitis.

Study CC-93538-EE-001 is a Phase 3, multicenter, multinational, randomized, double-blind, placebo-controlled induction and maintenance study to evaluate the efficacy and safety of CC- 93538 in adult and adolescent participants with eosinophilic esophagitis (EoE). The study will incorporate a 24-week Induction Phase followed by a 24-week Maintenance Phase. Participants will be …

Rocky Mountain Pediatric Gastroenterology
 (8.6 away) Contact site
  • 208 views
  • 21 Sep, 2022
  • +214 other locations
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib Administered Once Daily for 52 Weeks in Subjects With Non-Cystic Fibrosis Bronchiectasis - The ASPEN Study (ASPEN)

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

USA075
 (8.5 away) Contact site
  • 123 views
  • 20 Sep, 2022
  • +329 other locations
A Phase III, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Tildrakizumab in Subjects With Active Psoriatic Arthritis I (INSPIRE 1)

This is a multicenter Phase III, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of tildrakizumab in Subjects with Active Psoriatic Arthritis I (INSPIRE 1)

Sunpharma Site no 40
 (9.9 away) Contact site
  • 6 views
  • 22 Sep, 2022
  • +40 other locations
Fixed-Dose Trial in Early Parkinson's Disease (TemPo-1)

The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early Parkinson's Disease.

mao-b inhibitor
impulse control disorder
dementia
cognitive impairment
tremor
Rocky Mountain Movement Disorder Center
 (3.4 away) Contact site
  • 86 views
  • 21 Sep, 2022
  • +49 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer (SOLARIS)

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

folfiri
hydrochlorothiazide
corticosteroids
liver metastasis
adjuvant therapy
Rocky Mountain Cancer Centers-Littleton
 (1.2 away) Contact site
  • 148 views
  • 09 Aug, 2022
  • +883 other locations
Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian (PROFECTA-II)

Afuresertib is an AKT inhibitor, a new class of agents under development that may provide physicians with a new clinical option to control platinum resistant ovarian cancer (PROC) progression. Afuresertib plus chemotherapy has demonstrated anti-tumor efficacy and an acceptable safety profile in patients with PROC in a published Phase I/II …

Southwest Women's Oncology Group
 (324.5 away) Contact site
  • 21 views
  • 10 Aug, 2022
  • +46 other locations
Phase 2 Clinical Trial to Evaluate OC-01 Nasal Spray in Subjects With Neurotrophic Keratopathy

The objective of this study is to evaluate the safety and effectiveness of OC-01 (varenicline) nasal spray as compared to placebo nasal spray for mean change from baseline in corneal fluorescein staining in subjects with Stage 1 (corneal epithelial hyperplasia/punctate keratopathy) neurotrophic keratopathy (NK) in one or both eyes.

Littleton, Colorado
 (1.8 away) Contact site
  • 0 views
  • 11 Aug, 2022
  • +27 other locations
A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)

This is a double-blind, saline-controlled, and randomized study with blinded assessments using a single dose. Subjects that have a current diagnosis of chronic lumbar disc disease and meet eligibility criteria will be enrolled. Chronic lumbar disc disease is defined as back and/or radicular pain with degeneration of the disc confirmed …

Denver Back Pain Specialists, LLC
 (7.2 away) Contact site
  • 0 views
  • 11 Aug, 2022
  • +13 other locations