Littleton, Colorado Clinical Trials

A listing of Littleton, Colorado clinical trials actively recruiting patient volunteers.

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Found 374 clinical trials
An Open-Label, Long-term Study of GFB-887 in Patients With Glomerular Kidney Diseases

This is an open-label Phase 2 study evaluating the long term safety and tolerability of GFB-887 in patients with focal segmental glomerulosclerosis (FSGS), and treatment-resistant minimal change disease (TR-MCD)

segmental glomerulosclerosis
focal segmental glomerulosclerosis
minimal change disease
Colorado Kidney Care (Denver Nephrology)
 (9.9 away) Contact site
  • 07 Oct, 2022
  • +16 other locations
ORIN1001 in Patients With Advanced Solid Tumors and Relapsed Refractory Metastatic Breast Cancer

This study evaluates the anti-tumor effects of ORIN 1001 in patients with advanced solid tumors or relapsed refractory metastatic breast cancer (patients with progressive disease after receiving at least two lines of therapy in the advanced setting).

platelet count
measurable disease
her2-negative breast cancer
Highlands Ranch Hospital
 (4.5 away) Contact site
  • 04 Oct, 2022
  • +15 other locations
Evaluation of RRFT for Co-occurring SUD and PTSD Among Teens

Psychosocial traumatic events during childhood, serve as strong and consistent predictors of substance use problems (SUP) during adolescence and adulthood.PTSD that extends from such trauma often co-occurs with SUP. Despite this well-established link, standard care for adolescents with co-occurring SUP and PTSD for the last several decades has been to …

sexual abuse
behavioral therapy
behavior therapy
ARTS - Synergy Outpatient Services
 (2.7 away) Contact site
  • 04 Oct, 2022
  • +2 other locations
FT576 in Subjects With Multiple Myeloma

This is a Phase I dose-finding study of FT576 as monotherapy and in combination with the monoclonal antibody daratumumab in multiple myeloma (MM). The study will consist of a dose-escalation stage and an expansion stage.

measurable disease
Colorado Blood Cancer Institute
 (8.6 away) Contact site
  • 04 Oct, 2022
  • +4 other locations
Prosperando: Fostering Resilience on Dialysis

Latinos with End-Stage Renal Disease (ESRD) represent 17% of the US adult ESRD community and suffer a disproportionate burden of social challenges that impacts their well-being. With support from the Amos award from the Robert Wood Johnson Foundation (RWJF), the investigators assessed the feasibility of a 1-arm intervention of a …

Accepts healthy volunteers
Fresenius Medical Care Rocky Mountain Dialysis
 (9.6 away) Contact site
  • 04 Oct, 2022
  • 1 location
Testing the Addition of an Anti-Cancer Immunotherapy Drug, Avelumab, to Gemcitabine and Carboplatin Chemotherapy Prior to Surgery in Muscle Invasive Urinary Tract Cancer vs. Surgery Alone in Patients Who Are Not Able to Receive Cisplatin Therapy (SWOG GAP TRIAL)

This phase II trial studies the effect of avelumab, gemcitabine and carboplatin before surgery compared with surgery alone in treating patients with muscle invasive bladder or upper urinary tract cancer who are not able to receive cisplatin therapy. Immunotherapy with monoclonal antibodies, such as avelumab, may help the body's immune …

UCHealth Highlands Ranch Hospital
 (4.5 away) Contact site
  • 04 Oct, 2022
  • +65 other locations
A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors

The purpose of this study is to determine the maximum-tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of JBI-802 in patients with Advanced Solid Tumors.The efficacy of the RP2D will be evaluated in phase 2 in patients with solid tumors of neuroendocrine differentiation.

Sarah Cannon Research Institute at HealthONE
 (8.6 away) Contact site
  • 04 Oct, 2022
  • +3 other locations
Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

This phase II/III trial compares the effect of the combination of high-dose cisplatin every three weeks and radiation therapy versus low-dose cisplatin weekly and radiation therapy for the treatment of patients with locoregionally advanced head and neck cancer. Chemotherapy drugs, such as cisplatin, work in different ways to stop the …

Littleton Adventist Hospital
 (3.9 away) Contact site
  • 04 Oct, 2022
  • +100 other locations
Phase 1 Study of RBN-2397, an Oral PARP7 Inhibitor, in Patients With Solid Tumors

RBN-2397 inhibits PARP7, an enzyme that is switched on by cancer stresses, such as the toxins in cigarette smoke. Cancer cells use PARP7 to hide from the immune system by stopping the cell from sending a signal (Type 1 interferon) that tells the immune system that something is wrong and …

solid tumour
breast cancer
solid tumor
 (8.6 away) Contact site
  • 04 Oct, 2022
  • +14 other locations
CAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)

The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors

solid tumour
renal function test
measurable disease
triple negative breast cancer
Sarah Cannon Research Institute at Health One
 (8.6 away) Contact site
  • 04 Oct, 2022
  • +39 other locations