Lafayette, Colorado Clinical Trials

A listing of Lafayette, Colorado clinical trials actively recruiting patient volunteers.

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Found 59 clinical trials
Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

This randomized phase II trial studies how well ruxolitinib phosphate, and bosutnib, dasatinib, imatinib or nilotinib, work in treating patients with chronic myeloid leukemia. Chronic myeloid leukemia cells produce a protein called BCR-ABL. The BCR-ABL protein helps chronic myeloid leukemia cells to grow and divide. Tyrosine kinase inhibitors, such as …

Boulder Community Foothills Hospital
 (6.2 away) Contact site
  • 56 views
  • 30 May, 2022
  • +391 other locations
A Phase 3 Study to Assess the Safety and Efficacy of Pitolisant in Adult Patients With Idiopathic Hypersomnia

The primary objective of this study is to evaluate the safety and efficacy of pitolisant compared with placebo in treating excessive daytime sleepiness (EDS) in patients with idiopathic hypersomnia (IH) age ≥18 years. Key secondary objectives of this study are to assess the impact of pitolisant on: Overall symptoms of …

sleepiness
sleep disorders
modafinil
excessive daytime sleepiness
Alpine Clinical Research Center
 (7.6 away) Contact site
  • 3 views
  • 28 Jun, 2022
  • +4 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer (SOLARIS)

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

rifampin
cancer treatment
adjuvant therapy
metastatic colorectal adenocarcinoma
liver metastasis
Good Samaritan Medical Center
 (0.5 away) Contact site
  • 148 views
  • 22 Jul, 2022
  • +914 other locations
Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses (CREDIT)

This clinical trial examines a financial navigation program in helping patients and their spouses understand and better manage the financial aspects of cancer care. Cancer patients and their spouses may be at high risk for financial problems because of the cost of cancer treatment. A financial navigator is a person …

cancer
solid tumor
bone marrow transplant
experimental drug
Accepts healthy volunteers
Rocky Mountain Cancer Centers-Thornton
 (9.8 away) Contact site
  • 8 views
  • 20 Apr, 2022
  • +73 other locations
A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Assess STS101 in the Acute Treatment of Migraine (SUMMIT)

Study STS101-007 is a randomized, double-blind, parallel group, placebo-controlled, multicenter study to evaluate the efficacy, safety, and tolerability of single doses of STS101 (dihydroergotamine nasal powder) in the acute treatment of migraine.

headache
acute treatment
dihydroergotamine
Alpine Clinical Research Center, Inc
 (7.0 away) Contact site
  • 54 views
  • 06 May, 2022
  • +113 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

renal function
sentinel node
probe
biomarker analysis
adenocarcinoma of the breast
Kaiser Permanente-Rock Creek
 (0.5 away) Contact site
  • 1024 views
  • 17 May, 2022
  • +788 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

Kaiser Permanente-Rock Creek
 (0.5 away) Contact site
  • 288 views
  • 20 Jun, 2022
  • +441 other locations
Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by Annualized rate of acute moderate or severe COPD exacerbation (AECOPD) Secondary Objectives: To evaluate the effect of dupilumab administered every 2 weeks on Pre-bronchodilator …

Investigational Site Number :8400018
 (0.2 away) Contact site
  • 51 views
  • 17 Jun, 2022
  • +319 other locations
Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by Annualized rate of acute moderate or severe COPD exacerbation (AECOPD) Secondary Objectives: To evaluate the effect of dupilumab administered every 2 weeks on Pre-bronchodilator …

severe chronic obstructive pulmonary disease
muscarinic antagonists
corticosteroids
bronchitis
dyspnea
Investigational Site Number :8400018
 (0.2 away) Contact site
  • 305 views
  • 02 Jul, 2022
  • +315 other locations
Study in Subjects With Relapsed/Refractory Follicular Lymphoma

This is a multicenter, double-blind, active-controlled, randomized, 3-stage, biomarker enrichment design featuring early futility stopping and sample-size re-estimation with safety run-in designed to evaluate the efficacy and safety of tazemetostat in combination with lenalidomide and rituximab (R2) in subjects with relapsed or refractory (R/R) follicular lymphoma (FL), who have completed …

Rocky Mountain Cancer Centers (RMCC) - Boulder
 (6.2 away) Contact site
  • 2 views
  • 15 Jul, 2022
  • +104 other locations