Grand Junction, Colorado Clinical Trials

A listing of Grand Junction, Colorado clinical trials actively recruiting patient volunteers.

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Found 38 clinical trials
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery (ASPIRE)

Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF). Secondary Aim: To determine if apixaban, compared with aspirin, results in better functional outcomes …

apixaban
electrocardiogram
intracerebral hemorrhage
aspirin
atrial flutter
St. Mary's Medical Center
 (0.8 away) Contact site
  • 84 views
  • 21 Apr, 2022
  • +117 other locations
AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke (ARCADIA)

Objectives Primary: To test the hypothesis that apixaban is superior to aspirin for the prevention of recurrent stroke in patients with cryptogenic ischemic stroke and atrial cardiopathy. Secondary: To test the hypothesis that the relative efficacy of apixaban over aspirin increases with the severity of atrial cardiopathy.

infarct
aspirin
ischemic stroke
heart disease
hemorrhagic stroke
St. Mary's Medical Center
 (1.0 away) Contact site
  • 416 views
  • 26 Apr, 2022
  • +135 other locations
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, …

platelet count
paclitaxel
adenocarcinoma of the breast
breast adenocarcinoma
gilbert's syndrome
Saint Mary's Hospital and Regional Medical Center
 (1.0 away) Contact site
  • 1024 views
  • 17 May, 2022
  • +788 other locations
Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID) (ORCHID)

This is a randomized, double-blind, placebo-controlled, parallel-group, international, multicenter, Phase 3 study to evaluate the efficacy and safety of repeat dosing of benralizumab 30 mg administered subcutaneously (SC) versus placebo in patients with severe nasal polyposis.

rhinosinusitis
polyposis
asthma
benralizumab
aspirin
Research Site
 (1.0 away) Contact site
  • 22 views
  • 05 Jul, 2022
  • +83 other locations
Study in Subjects With Relapsed/Refractory Follicular Lymphoma

This is a multicenter, double-blind, active-controlled, randomized, 3-stage, biomarker enrichment design featuring early futility stopping and sample-size re-estimation with safety run-in designed to evaluate the efficacy and safety of tazemetostat in combination with lenalidomide and rituximab (R2) in subjects with relapsed or refractory (R/R) follicular lymphoma (FL), who have completed …

St. Mary's Hospital and Regional Medical Center - St. Mary's
 (0.8 away) Contact site
  • 2 views
  • 15 Jul, 2022
  • +104 other locations
Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6) (SERENA-6)

The study is intended to show superiority of AZD9833 in combination with CDK4/6 inhibitor (palbociclib or abemaciclib) versus aromatase inhibitors (anastrozole or letrozole) in combination with CDK4/6 inhibitor in patients with hormone receptor-positive (HR-positive), human epidermal growth factor receptor 2-negative (HER2-negative) metastatic breast cancer with detectable ESR1 mutation

Research Site
 (1.0 away) Contact site
  • 35 views
  • 23 Jul, 2022
  • +137 other locations
A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

This Phase III, randomized, double-blind, placebo-controlled, multicenter study will evaluate the efficacy and safety of giredestrant combined with palbociclib compared with letrozole combined with palbociclib in patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor-2 (HER2)-negative locally advanced (recurrent or progressed) or metastatic breast cancer.

St Mary's Hospital and Medical Center
 (0.9 away) Contact site
  • 1 views
  • 25 Jul, 2022
  • +289 other locations
Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

This study will look at the efficacy and safety of trastuzumab deruxtecan (T-DXd) in a neoadjuvant setting, in high-risk, HER2-positive early non-metastatic breast cancer.

paclitaxel
doxorubicin
mammogram
inflammatory breast cancer
magnetic resonance imaging of breast
Research Site
 (1.0 away) Contact site
  • 4 views
  • 21 Jul, 2022
  • +63 other locations
Randomized Study in Children and Adolescents With Migraine: Acute Treatment

The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.

acute treatment
migraine in children
erenumab
Boeson Research GJT
 (0.8 away) Contact site
  • 13 views
  • 29 Jul, 2022
  • +120 other locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such …

paclitaxel
hepatitis b
mammogram
trastuzumab
chemotherapy drug
Grand Valley Oncology
 (1.0 away) Contact site
  • 92 views
  • 27 Jul, 2022
  • +639 other locations