Denver, Colorado Clinical Trials

A listing of Denver, Colorado clinical trials actively recruiting patient volunteers.

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Found 178 clinical trials
The ARIES HeartMate 3 Pump IDE Study

Prospective, randomized, double-blinded, placebo-controlled clinical investigation of advanced heart failure patients treated with the HM3 with two different antithrombotic regimens: vitamin K antagonist with aspirin versus vitamin K antagonist with placebo

heart failure
aspirin
University of Colorado Hospital
 (8.1 away) Contact site
  • 8 views
  • 11 Aug, 2022
  • +47 other locations
A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Patients 6 to 17 Years of Age

The primary objective of the study is to evaluate the effectiveness of fremanezumab as compared to placebo for the preventive treatment of chronic migraine (CM). Secondary objectives are to further demonstrate the efficacy of Fremanezumab as compared to placebo for the preventive treatment of CM, to evaluate the safety and …

fremanezumab
daily headaches
chronic migraine
recurrent headaches
headache
Teva Investigational Site 14319
 (8.2 away) Contact site
  • 302 views
  • 10 Aug, 2022
  • +74 other locations
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of …

metastasis
docetaxel
intensity-modulated radiation therapy
gilbert's syndrome
tumor cells
Porter Adventist Hospital
 (4.6 away) Contact site
  • 109 views
  • 11 Aug, 2022
  • +129 other locations
Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery

This phase II/III trial studies how well circulating tumor deoxyribonucleic acid (ctDNA) testing in the blood works in predicting treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there …

calcium
colon cancer
platelet count
leucovorin
oxaliplatin
Colorado Blood Cancer Institute
 (1.1 away) Contact site
  • 0 views
  • 10 Aug, 2022
  • +593 other locations
Pan Tumor Nivolumab Rollover Study

Main Objective of this study is to examine long-term safety of nivolumab in participants on treatment and in follow up.

nivolumab
University of Colorado
 (8.1 away) Contact site
  • 10 views
  • 12 Aug, 2022
  • +152 other locations
A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML) (VIALE-T)

The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Relapse Free Survival (RFS) in Acute Myeloid Leukemia (AML) participants compared to Best Supportive Care (BSC) when given as maintenance therapy following allogeneic stem cell transplantation (SCT). This study will have …

blast cells
bone marrow procedure
venetoclax
azacitidine
cell transplantation
Colorado Blood Cancer Institute /ID# 215980
 (1.1 away) Contact site
  • 96 views
  • 10 Aug, 2022
  • +112 other locations
CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

To evaluate the efficacy of eplontersen compared to placebo in participants with ATTR-CM receiving available standard of care (SoC). For more information, please visit https://www.cardio-ttransform.com.

University of Colorado Hospital - Anschutz Medical Campus
 (8.1 away) Contact site
  • 12 views
  • 08 Aug, 2022
  • +150 other locations
A Study of Oral Venetoclax Tablets and Oral Azacitidine Versus Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy (VIALE-M)

This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in combination with AZA. Part 3 will be conducted in 2 phases - Dose Finding portion to determine RPTD of venetoclax in combination with CC-486 …

cancer
venetoclax
azacitidine
consolidation chemotherapies
remission
Colorado Blood Cancer Institute /ID# 214280
 (1.1 away) Contact site
  • 49 views
  • 08 Aug, 2022
  • +134 other locations
Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

The purpose of this study is to determine if Rozibafusp Alfa could be a useful therapeutic agent in the current treatment landscape where subjects with systemic lupus erythematosus (SLE) have ongoing disease activity despite treatment with standard of care therapies.

hydroxychloroquine
nephritis
methotrexate
mycophenolate
antinuclear antibody
University of Colorado Denver
 (8.1 away) Contact site
  • 101 views
  • 08 Aug, 2022
  • +126 other locations
A Phase 1 Open-label, Multicenter, Dose Escalation Study of the Safety, Tolerability, and PK of HPN217 in Patients With R/R MM

An open-label, Phase 1 study of HPN217 to assess the safety, tolerability and PK in patients with relapsed/ refractory multiple myeloma

measurable disease
platelet count
proteasome inhibitor
neutrophil count
renal function
Colorado Blood Cancer Institute
 (1.1 away) Contact site
  • 40 views
  • 11 Aug, 2022
  • +14 other locations