Denver, Colorado Clinical Trials

A listing of Denver, Colorado clinical trials actively recruiting patient volunteers.

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Found 834 clinical trials
Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (HERCULES)

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in NRSPMS Secondary Objective: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety and tolerability of SAR442168 …

secondary progressive multiple sclerosis
Investigational Site Number :8400012
 (2.0 away) Contact site
  • 31 views
  • 11 Jul, 2022
  • +277 other locations
An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab (ARTIOS)

Open-label study to evaluate the effectiveness of treatment with ofatumumab in subjects transitioning from any fumarate-based RMS approved therapy or fingolimod due to breakthrough disease.

dimethyl fumarate
fingolimod
ofatumumab
Novartis Investigative Site
 (8.1 away) Contact site
  • 183 views
  • 12 Jul, 2022
  • +136 other locations
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance. The study will …

Novo Nordisk Investigational Site
 (1.1 away) Contact site
  • 0 views
  • 01 Jun, 2022
  • +43 other locations
The SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma (STEM) (STEM)

STEM Study is a pivotal, international, multi-center, prospective, randomized (1:1) controlled trial designed to provide an assessment of the safety and effectiveness of Middle Meningeal Artery (MMA) embolization with SQUID for the management of Chronic Subdural Hematoma (cSDH)

Swedish Medical Center
 (7.0 away) Contact site
  • 15 views
  • 16 Jun, 2022
  • +25 other locations
Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal Treatment (SPLASH)

The purpose of this study is to evaluate the efficacy and safety of [Lu-177]-PNT2002 in patients with metastatic castration-resistant prostate cancer who have progressed following treatment with androgen receptor axis-targeted therapy (ARAT).

University of Colorado Hospital
 (8.1 away) Contact site
  • 0 views
  • 16 Jun, 2022
  • +37 other locations
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC) (VISTAS)

The purpose of this clinical research study is to learn more about the use of the study medicine, volixibat, for the treatment of pruritus (itching) associated with Primary Sclerosing Cholangitis (PSC), and to assess the possible impact on the disease progression of PSC.

University of Colorado - Anschutz Medical Campus
 (8.1 away) Contact site
  • 0 views
  • 16 Jun, 2022
  • +30 other locations
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer

This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.

Accepts healthy volunteers
The Women's Imaging Center
 (2.9 away) Contact site
  • 2688 views
  • 02 Jul, 2022
  • +76 other locations
A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat

The primary objective of the study is to determine the efficacy of REGN1908-1909, as compared to placebo, to reduce allergic rhinitis/conjunctivitis symptoms and allergy rescue medication use during natural cat exposure. The Secondary Objectives are: To assess the reduction of allergic symptoms and use of allergy rescue medications after treatment …

Colorado Allergy and Asthma Centers PC - CRN - PPDS
 (5.5 away) Contact site
  • 3 views
  • 03 Jul, 2022
  • +83 other locations
Study of Sotatercept in Newly Diagnosed Intermediate- and High-risk PAH Patients (HYPERION)

The objective of this study is to evaluate the effects of sotatercept treatment (plus background PAH therapy) versus placebo (plus background PAH therapy) on time to clinical worsening (TTCW) in participants who are newly diagnosed with PAH and are at intermediate or high risk of disease progression.

University of Colorado Hospital ( Site 1013)
 (8.2 away) Contact site
  • 0 views
  • 13 Jul, 2022
  • +75 other locations
ADCC Mediated B-Cell dEpletion and BAFF-R Blockade (AMBER)

VAY736 dose testing; VAY736 efficacy and safety testing.

adcc
Novartis Investigative Site
 (2.8 away) Contact site
  • 135 views
  • 13 Jul, 2022
  • +41 other locations