Aurora, Colorado Clinical Trials

A listing of Aurora, Colorado clinical trials actively recruiting patient volunteers.

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Found 1314 clinical trials
Featured trial
An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

Our team of medical professionals is evaluating an investigational drug that is designed to slow the progression of Alzheimer’s disease. The study drug, ALZ-801, is a tablet that is taken twice daily. It has been well tolerated in earlier studies and may be a convenient option for Alzheimer’s patients and …

dementia
mini-mental state examination
mild dementia
apolipoprotein e
Mile High Research Center
 (7.4 away) Contact site
  • 76 views
  • 12 Jul, 2022
  • +78 other locations
Featured trial
A Study to Assess the Safety of BIIB122 Tablets and if it Can Slow the Worsening of Early-Stage Parkinson's Disease in Participants Between the Ages of 30 and 80

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). In this study: Participants will take 225 milligrams (mg) of BIIB122 or a placebo as tablets by mouth. A placebo looks like the study drug but has no real medicine …

hoehn and yahr scale
movement disorder
CenExel Rocky Mountain Movement Disorders Center
 (9.3 away) Contact site
  • 3 views
  • 13 Jul, 2022
  • +3 other locations
Featured trial
INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma

The purpose of this study is to evaluate the safety and antitumor activity of INCB001158 in combination with daratumumab SC, compared with daratumumab SC alone, in participants with relapsed or refractory multiple myeloma who have received at least 3 but not more than 5 prior lines of multiple myeloma therapy. …

refractory multiple myeloma
daratumumab
ROCKY MOUNTAIN CANCER CENTER
 (7.4 away) Contact site
  • 186 views
  • 10 May, 2022
  • +27 other locations
Featured trial
A Phase 2 Study of INCMGA00012 (PD-1 Inhibitor) in Participants With Selected Solid Tumors (POD1UM-203)

The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with advanced solid tumors where the efficacy of PD-1 inhibitors has previously been established.  

solid tumors
solid tumor
Rocky Mountain Cancer Centers, LLP
 (7.4 away) Contact site
  • 84 views
  • 10 May, 2022
  • +52 other locations
Featured trial
Study to evaluate TEPEZZA® in patients with Chronic (Inactive) Thyroid Eye Disease (TED)

The goal is to determine the efficacy, safety and tolerability of TEPEZZA® for treating chronic (inactive) TED. About 57 participants will start with a 24-week treatment period. Patients that do not meet the desired response after the 24-week treatment period may receive up to 8 additional infusions of TEPEZZA®.  After …

Univ of Colorado Dept of Ophthalmology
 (1.5 away) Contact site
  • 13 views
  • 20 May, 2022
  • +8 other locations
Featured trial
Study in Parkinson Disease of Exercise (SPARX3)

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax …

SPECT Scan
movement disorder
datscan
University of Colorado, Denver
 (1.2 away) Contact site
  • 162 views
  • 07 Jun, 2022
  • +25 other locations
Featured trial
An Open-Label Phase 2 Study of Itacitinib (INCB039110) in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Subjects With Myelofibrosis

The purpose of this study is to evaluate the efficacy and safety of itacitinib combined with low-dose ruxolitinib or itacitinib alone in subjects with myelofibrosis.   This is an open-label Phase 2 study with 2 cohorts: Cohort A: Itacitinib plus ruxolitinib  Drug: Itacitinib self-administered orally once daily at the   protocol-defined …

myeloproliferative disorders
myelofibrosis
leukemia
ANSCHUTZ CANCER PAVILION - UNIVERSITY OF COLORADO
 (0.9 away) Contact site
  • 172 views
  • 10 May, 2022
  • +8 other locations
Featured trial
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

Evaluates the safety, tolerability, pharmacokinetics, metabolites, pharmacodynamics, and clinical activity of MRTX849 in patients with advanced solid tumors with a KRAS G12C mutation. MRTX849 is an orally-available small molecule inhibitor of KRAS G12C.

advanced solid tumor
malignant solid tumor
solid tumor
Mirati Research Site
 (1.5 away) Contact site
  • 538 views
  • 22 Nov, 2021
  • +61 other locations
Featured trial
Studies for the Treatment of Atopic Dermatitis (eczema)

Studies for the Treatment of Atopic Dermatitis (eczema)

Horizons Clinical Research Center, LLC
 (4.3 away) Contact site
  • 840 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Research Studies for the Treatment of ACNE

Research Studies for the Treatment of ACNE

Horizons Clinical Research Center, LLC
 (4.3 away) Contact site
  • 686 views
  • 08 Nov, 2020
  • 1 location