Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 74 clinical trials
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body (metastatic). Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor …

staining intensity
platelet count
metastasis
pertuzumab
tumor cells
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 438 views
  • 02 Dec, 2020
  • +404 other locations
Iobenguane I-131 or Crizotinib and Standard Therapy in Treating Younger Patients With Newly-Diagnosed High-Risk Neuroblastoma or Ganglioneuroblastoma

This phase III trial studies iobenguane I-131 or crizotinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Crizotinib may stop the growth of tumor cells by blocking …

dinutuximab
etoposide
tumor cells
high-risk neuroblastoma
iobenguane
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 66 views
  • 02 Dec, 2020
  • +95 other locations
Safety Immunogenicity and Hemostatic Efficacy of PEGylated Recombinant FVIII (BAX 855) in Previously Untreated Patients (PUPs) < 6 Years of Age With Severe Hemophilia A

The purpose of this study is to investigate safety, immunogenicity and hemostatic efficacy of PEGylated recombinant FVIII (BAX 855) in previously untreated patients (PUPs) < 6 years of age with severe hemophilia A (baseline FVIII level < 1%) and < 3 EDs to ADVATE, BAX 855 or plasma transfusion.

bax 855
recombinant factor viii
antihemophilic factor
severe haemophilia a
advate
Kaiser Permanente Oakland M.C.
 (9.6 away) Contact site
  • 0 views
  • 02 Aug, 2020
  • +102 other locations
Recent-Onset Type 1 Diabetes Trial Evaluating Efficacy and Safety of Teplizumab

The purpose of this study is to determine whether teplizumab slows the loss of cells and preserves cell function in children and adolescent 8-17 years old who have been diagnosed with T1D in the previous 6 weeks.. Subjects will receive two courses of either teplizumab or placebo treatment 6 months …

tolerance test
c-peptide
diabetes
Clinical Site
 (2.2 away) Contact site
  • 320 views
  • 26 Oct, 2020
  • +107 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

lung cancer
live vaccine
carboplatin
hepatitis c virus
immunosuppressive
Kaiser Permanente-Walnut Creek
 (2.8 away) Contact site
  • 206 views
  • 02 Dec, 2020
  • +777 other locations
Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

The purpose of this study is to assess the efficacy and safety of treatment with carboplatin/paclitaxel* PLUS pembrolizumab (MK-3475) and maintenance olaparib (MK-7339) in women with epithelial ovarian cancer (EOC), fallopian tube cancer, or primary peritoneal cancer. The primary study hypotheses are that the combination of pembrolizumab plus carboplatin/paclitaxel* followed …

bevacizumab
epithelial ovarian cancer
excisional biopsy
carboplatin
BRCA1
Kaiser Permanente Oncology Clinical Trial - Walnut Creek ( Site 0080)
 (2.8 away) Contact site
  • 732 views
  • 02 Dec, 2020
  • +244 other locations
Ibrutinib and Obinutuzumab With or Without Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia

This phase III trial studies how well ibrutinib and obinutuzumab with or without venetoclax work in treating patients with chronic lymphocytic leukemia. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Obinutuzumab is a monoclonal antibody that may interfere with the …

venetoclax
anemia
chronic lymphocytic leukemia
gilbert's syndrome
lymphoma
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 624 views
  • 02 Dec, 2020
  • +714 other locations
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The study will be performed in people with type 2 diabetes. Participants will either get semaglutide or placebo in addition to their diabetes medicines - which treatment the …

semaglutide
hypoglycemic agents
Novo Nordisk Investigational Site
 (2.2 away) Contact site
  • 581 views
  • 22 Nov, 2020
  • +233 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

cyclophosphamide
metastasis
emetics
vomiting
nausea
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 109 views
  • 22 Nov, 2020
  • +563 other locations
Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy

This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the …

axillary lymph node dissection
ductal carcinoma in situ
metastatic disease
residual tumor
ductal carcinoma
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 508 views
  • 27 May, 2020
  • +702 other locations