Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 75 clinical trials
Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy

The purpose of this study is to evaluate the efficacy and safety of intramuscular (IM) administration of Engensis on pain in participants with painful diabetic peripheral neuropathy (DPN) in the feet and lower legs, as compared to Placebo, as a second Phase 3, well controlled study, sufficient in supporting the …

Diablo Clinical Research
 (2.2 away) Contact site
  • 0 views
  • 20 Nov, 2020
  • +4 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

metastasis
monoclonal antibodies
measurable disease
major surgery
vitamin d
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 65 views
  • 20 Nov, 2020
  • +887 other locations
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

This phase III trial studies response-based chemotherapy in treating newly diagnosed acute myeloid leukemia or myelodysplastic syndrome in younger patients with Down syndrome. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by …

etoposide
cytarabine
cytopenia
trisomy
leukemia
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 153 views
  • 27 Sep, 2020
  • +133 other locations
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

This randomized phase III trial studies how well standard-dose combination chemotherapy works compared to high-dose combination chemotherapy and stem cell transplant in treating patients with germ cell tumors that have returned after a period of improvement or did not respond to treatment. Drugs used in chemotherapy, such as paclitaxel, ifosfamide, …

chemotherapy drugs
etoposide
cancer chemotherapy
ifosfamide
g-csf
Kaiser Permanente-Oakland
 (9.2 away) Contact site
  • 803 views
  • 22 Nov, 2020
  • +89 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

myocardial infarction
acute coronary syndrome
infarct
stroke
percutaneous coronary intervention
8400891 - John Muir Medical Center Walnu
 (2.2 away) Contact site
  • 1118 views
  • 25 Nov, 2020
  • +3405 other locations
Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

This randomized phase III trial studies how well pembrolizumab works in treating patients with triple-negative breast cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

metastasis
invasive cancer
estrogen receptor
monoclonal antibodies
oophorectomy
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 1080 views
  • 25 Nov, 2020
  • +612 other locations
Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

This phase III trial compares nephrectomy (surgery to remove a kidney or part of a kidney) with nivolumab to the usual approach of nephrectomy followed by standard post-operative follow-up and monitoring, in treating patients with kidney cancer that is limited to a certain part of the body (localized). Nivolumab is …

nivolumab
renal function tests
metastasis
primary tumor
monoclonal antibodies
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 351 views
  • 25 Nov, 2020
  • +258 other locations
S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer

This randomized phase III trial studies Tokyo-172 strain bacillus Calmette-Guerin (BCG) solution with or without a vaccination using Tokyo-172 strain BCG to see how well it works compared with TICE BCG solution in treating patients with bladder cancer that has not spread to muscle. BCG is a non-infectious bacteria that …

Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 222 views
  • 25 Nov, 2020
  • +198 other locations
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

This randomized phase III trial studies how well combination chemotherapy (vincristine sulfate, dactinomycin, cyclophosphamide alternated with vincristine sulfate and irinotecan hydrochloride or vinorelbine) works compared to combination chemotherapy plus temsirolimus in treating patients with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle), and has an intermediate chance …

vinorelbine
cancer chemotherapy
neutrophil count
cancer
irinotecan
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 292 views
  • 25 Nov, 2020
  • +268 other locations
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body (metastatic). Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor …

metastasis
ejection fraction
paclitaxel
estrogen receptor
monoclonal antibodies
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 438 views
  • 25 Nov, 2020
  • +404 other locations