Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 52 clinical trials
Safety Tolerability and Efficacy of the Human Cytomegalovirus Vaccine (V160) in Healthy Women 16 to 35 Years of Age (V160-002)

This study will evaluate the safety, tolerability, and efficacy of Human Cytomegalovirus (CMV) vaccine V160 administered in a 2-dose or 3-dose regimen in healthy seronegative women 16 to 35 years of age. Participants will receive blinded V160 on Day 1, Month 2, and Month 6 (3-dose regimen), V160 on Day …

Diablo Clinical Research, Inc ( Site 0009)
 (2.2 away) Contact site
  • 6476 views
  • 12 Aug, 2019
  • +95 other locations
Open-label Multicenter Extension Study to Evaluate Long-term Safety and Tolerability of LOU064 in Subjects With CSU

This study is an open-label, single arm, multicenter, long-term safety and tolerability extension study for CSU patients who completed CLOU064A2201 or other preceding studies with LOU064

Novartis Investigative Site
 (4.7 away) Contact site
  • 0 views
  • 26 Oct, 2020
  • +52 other locations
Multiple Dose Study to Evaluate the Efficacy Safety and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus

This is a randomized, placebo-controlled, double-blind study to evaluate the efficacy, safety, and pharmacodynamics (PD) of multiple doses of REMD-477 in subjects who have Type 1 diabetes and are currently receiving insulin treatment. This study will determine whether REMD-477 can decrease daily insulin requirements and improve glycemic control after 12 …

Diablo Clinical Research
 (2.2 away) Contact site
  • 866 views
  • 21 Oct, 2020
  • +10 other locations
Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status

This is a phase II trial to examine the efficacy of neratinib plus trastuzumab or neratinib plus cetuximab in patients with "quadruple wild-type" (all RAS/NRAS/BRAF/PIK3CA wild-type), metastatic colorectal cancer based on HER2 status (amplified, non-amplified [wild-type] or mutated). Patients must have confirmed quadruple wild-type (WT) genotype, via NSABP MPR-1 or …

KRAS
metastasis
cetuximab
irinotecan
BRAF
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 114 views
  • 27 Nov, 2020
  • +47 other locations
Pembrolizumab in Treating Patients With Desmoplastic Melanoma That Can or Cannot Be Removed by Surgery

This pilot phase II trial studies how well pembrolizumab works in treating patients with desmoplastic melanoma (DM) that can be removed by surgery (resectable) or cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere …

Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 91 views
  • 26 Nov, 2020
  • +193 other locations
Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid Leukemia

This phase II trial studies how stopping tyrosine kinase inhibitors will affect treatment-free remission in patients with chronic myeloid leukemia in chronic phase. When the level of disease is very low, it's called molecular remission. TKIs are a type of medication that help keep this level low. However, after being …

Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 2 views
  • 20 Aug, 2020
  • +24 other locations
High-dose Vitamin D Supplements in Older Adults

This Phase II randomized clinical trial aims to test if supplementation with high dose oral vitamin D will successfully correct vitamin D insufficiency, compared to treatment with standard (RDA) dose vitamin D in a diverse community-based elderly cohort. The effect of high-dose vs. standard-dose vitamin D on altering cognitive trajectories …

University of California, Davis Alzheimer's Disease Center
 (4.7 away) Contact site
  • 0 views
  • 23 Nov, 2020
  • 1 location
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphomas or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

olaparib
blood count
cytotoxic chemotherapy
cns tumor
samotolisib
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 990 views
  • 25 Nov, 2020
  • +111 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

metastasis
brain tumor
hysterectomy
corticosteroid
adrenaline
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 6087 views
  • 25 Nov, 2020
  • +967 other locations
Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)

This study will examine the safety and efficacy of pembrolizumab (MK-3475) in combination with chemotherapy in children and young adults with newly diagnosed classical Hodgkin Lymphoma (cHL) who are slow early responders (SERs) to frontline chemotherapy.

lymphoma
prednisone
doxorubicin
measurable disease
dacarbazine
Kaiser Permanente - Oakland ( Site 0047)
 (9.6 away) Contact site
  • 23 views
  • 05 Nov, 2020
  • +63 other locations