Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 62 clinical trials
Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

This phase II Lung-MAP trial studies how well rucaparib works in treating patients with genomic loss of heterozygosity (LOH) high and/or deleterious BRCA1/2 mutation stage IV non-small cell lung cancer or that has come back. Rucaparib may stop the growth of tumor cells by blocking some of the enzymes needed …

systemic chemotherapy
hysterectomy
MRI Scan
brain metastases
stage iv non-small cell lung cancer
Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 175 views
  • 09 May, 2021
  • +746 other locations
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. …

hormone therapy
cancer
brain metastases
nivolumab
tubal ligation
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 191 views
  • 22 Jun, 2021
  • +473 other locations
Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer

This phase II trial studies how well avelumab with or without cetuximab work in treating patients with skin squamous cell cancer that has spread to other places in the body. Immunotherapy with monoclonal antibodies, such as avelumab and cetuximab, may help the body's immune system attack the cancer, and may …

investigational drug
pd-l1
tumor cells
cancer
cetuximab
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 30 views
  • 18 Jun, 2021
  • +401 other locations
Genetic Testing in Guiding Treatment for Patients With Brain Metastases

This phase II trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain. Several genes have been found to be altered or mutated in brain metastases such as NTRK, ROS1, CDK or PI3K. Medications that target these genes such …

Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 142 views
  • 17 Jun, 2021
  • +378 other locations
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

This phase II trial studies how well the combination of dabrafenib and trametinib works after radiation therapy in children and young adults with high grade glioma who have a genetic change called BRAF V600 mutation. Radiation therapy uses high energy rays to kill tumor cells and reduce the size of …

MRI
dabrafenib
BRAF
ganglioglioma
cancer
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 129 views
  • 15 Jun, 2021
  • +53 other locations
A Phase 2 Durability of Response Study of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata

This is a two part, double-blind, randomized, multicenter study to evaluate the regrowth of hair with CTP-543 and subsequent durability of that regrowth following dose reduction in adult patients with moderate to severe alopecia areata.

areata alopecia
Kaiser Permanente
 (9.6 away) Contact site
  • 0 views
  • 22 Jun, 2021
  • +26 other locations
Docetaxel or Paclitaxel in Reducing Chemotherapy-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

This phase II trial studies how well docetaxel or paclitaxel work in reducing chemotherapy-induced peripheral neuropathy in African American patients with stages I-III breast cancer. Drugs used in chemotherapy, such as docetaxel and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, …

breast carcinoma
oophorectomy
docetaxel
hysterectomy
neuropathy
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 96 views
  • 16 Mar, 2021
  • +327 other locations
Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

This phase II trial studies the side effects and how well larotrectinib works in treating patients with previously untreated TRK fusion solid tumors and TRK fusion acute leukemia that has come back. Larotrectinib may stop the growth of cancer cells with TRK fusions by blocking the TRK enzymes needed for …

cancer
nephroblastoma
pegfilgrastim
leukemia
solid tumor
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 3 views
  • 31 May, 2021
  • +34 other locations
A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

This phase II trial studies how pembrolizumab works before and after surgery in treating patients with stage III-IV high-risk melanoma. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.. Giving …

Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 71 views
  • 21 Jun, 2021
  • +685 other locations
Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial)

This phase II LUNG-MAP treatment trial studies how well combination treatment (talazoparib plus avelumab) works in treating patients with non-squamous non-small cell lung cancer that has an STK11 gene mutation and has come back (recurrent) or is stage IV. Talazoparib may stop the growth of tumor cells by blocking some …

systemic chemotherapy
MRI Scan
p-gp
brain metastases
liver metastases
Kaiser Permanente-Walnut Creek
 (2.8 away) Contact site
  • 33 views
  • 25 Jan, 2021
  • +249 other locations