Walnut Creek, California Clinical Trials

A listing of Walnut Creek, California clinical trials actively recruiting patient volunteers.

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Found 59 clinical trials
A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

This phase II trial studies how pembrolizumab works before and after surgery in treating patients with stage III-IV high-risk melanoma. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving …

Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 71 views
  • 27 Nov, 2020
  • +656 other locations
Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer

This phase II trial studies how well avelumab with or without cetuximab work in treating patients with skin squamous cell cancer that has spread to other places in the body. Immunotherapy with monoclonal antibodies, such as avelumab and cetuximab, may help the body's immune system attack the cancer, and may …

neutrophil count
measurable disease
metastatic cutaneous squamous cell carcinoma
investigational drug
platelet count
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 30 views
  • 19 Nov, 2020
  • +338 other locations
Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)

This phase II Lung-MAP non-Match treatment trial studies how well ramucirumab and pembrolizumab work versus standard of care in treating patients with non-small cell lung cancer that is stage IV or has come back. Immunotherapy with monoclonal antibodies, such as ramucirumab and pembrolizumab, may help the body's immune system attack …

insulin
liver metastasis
tumor cells
metastasis
serum bilirubin
Kaiser Permanente-Walnut Creek
 (2.8 away) Contact site
  • 80 views
  • 20 Aug, 2020
  • +628 other locations
Ulixertinib in Treating Patients With Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well ulixertinib works in treating patients with solid tumors that have spread to other places in the body (advanced), non-Hodgkin lymphoma, or histiocytic disorders that have a genetic alteration (mutation) in a signaling pathway called MAPK. A signaling pathway consists of a …

neutrophil count
metastatic disease
radiopharmaceutical
cancer treatment
blood transfusion
Kaiser Permanente-Oakland
 (9.2 away) Contact site
  • 94 views
  • 23 Nov, 2020
  • +75 other locations
A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

This phase II trial studies how well axitinib and nivolumab work in treating patients with TFE/translocation renal cell carcinoma that cannot be removed by surgery (unresectable) or has spread to other places in the body (metastatic). Axitinib may stop the growth of tumor cells by blocking some of the enzymes …

neutrophil count
kidney cancer
measurable disease
direct bilirubin
platelet count
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 66 views
  • 27 Nov, 2020
  • +202 other locations
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone …

neutrophil count
orchiectomy
bicalutamide
prednisone
biomarker analysis
Epic Care Cyberknife Center
 (0.9 away) Contact site
  • 1518 views
  • 27 May, 2020
  • +440 other locations
PI3K/mTOR Inhibitor LY3023414 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well PI3K/mTOR inhibitor LY3023414 works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with TSC or PI3K/MTOR mutations that have spread to other places in the body (metastatic) and have come back (recurrent) or do not respond to treatment …

nervous system disorders
131i-mibg
seizure disorder
metastasis
hematopoietic growth factors
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 377 views
  • 28 Nov, 2020
  • +80 other locations
S1613 Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

This randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified colorectal cancer that has spread from where it started to other places in the body and cannot be removed by surgery. Monoclonal antibodies, such as trastuzumab …

neutrophil count
metastatic disease
braf gene
brain metastases
carcinoma in situ
Epic Care Cyberknife Center
 (0.7 away) Contact site
  • 419 views
  • 02 Mar, 2020
  • +769 other locations
Cisplatin Carboplatin and Etoposide or Temozolomide and Capecitabine in Treating Patients With Neuroendocrine Carcinoma of the Gastrointestinal Tract or Pancreas That Is Metastatic or Cannot Be Removed by Surgery

This randomized phase II trial studies how well temozolomide and capecitabine work compared to standard treatment with cisplatin or carboplatin and etoposide in treating patients with neuroendocrine carcinoma of the gastrointestinal tract or pancreas that has spread to other parts of the body (metastatic) or cannot be removed by surgery. …

Kaiser Permanente-Walnut Creek
 (0.7 away) Contact site
  • 697 views
  • 27 May, 2020
  • +406 other locations
Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well larotrectinib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with NTRK fusions that have spread to other places in the body and have come back or do not respond to treatment. Larotrectinib may stop the growth of …

neutrophil count
metastatic disease
radiopharmaceutical
cancer treatment
total body irradiation
Kaiser Permanente-Oakland
 (9.6 away) Contact site
  • 351 views
  • 23 Nov, 2020
  • +80 other locations